Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a
Physiological systems
22 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Integument Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system
15 No significant impact
2 Not tested
Data collections
Gene metrics:16Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
decreased circulating calcium level | 1 supporting dataset | Tnfrsf1atm2b(EUCOMM)Wtsi | homozygote | Late adult | 7.71x10-5 | ||
increased grip strength | 2 supporting datasets | Tnfrsf1atm2b(EUCOMM)Wtsi | homozygote | Late adult | 2.75x10-5 | ||
increased basophil cell number | 1 supporting dataset | Tnfrsf1atm2b(EUCOMM)Wtsi | homozygote | Late adult | 1.56x10-7 | ||
decreased neutrophil cell number | 1 supporting dataset | Tnfrsf1atm2b(EUCOMM)Wtsi | homozygote | Late adult | 2.83x10-5 | ||
abnormal heart morphology | 1 supporting dataset | Tnfrsf1aem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
increased lymphocyte cell number | 3 supporting datasets | Tnfrsf1atm2b(EUCOMM)Wtsi | homozygote | Late adult | 1.51x10-10 | ||
increased neutrophil cell number | 2 supporting datasets | Tnfrsf1aem1(IMPC)Ccpcz | homozygote | Early adult | 2.18x10-5 | ||
increased basophil cell number | 1 supporting dataset | Tnfrsf1atm2b(EUCOMM)Wtsi | homozygote | Early adult | 9.68x10-6 | ||
increased large unstained cell number | 1 supporting dataset | Tnfrsf1atm2b(EUCOMM)Wtsi | homozygote | Late adult | 5.49x10-5 | ||
increased effector memory CD8-positive, alpha-beta T cell number | 1 supporting dataset | Tnfrsf1aem1(IMPC)Ccpcz | homozygote | Early adult | 2.46x10-5 |
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External links
No external links available for Tnfrsf1a.
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Tnfrsf1aem1(IMPC)Ccpcz | Intra-exon deletion | | mouse |
Tnfrsf1atm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Tnfrsf1atm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Tnfrsf1atm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Tnfrsf1atm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Tnfrsf1atm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Tnfrsf1atm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |