Gene: Afdn

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Name
afadin, adherens junction formation factor
MGI ID
MGI:1314653
Synonyms
AF6 Afadin S-afadin I-afadin 5033403D15Rik Mllt4
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged lymph nodes Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal uterus morphology Afdnem1(IMPC)Mbp HET Early adult 0.00
abnormal cecum morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
small spleen Afdnem1(IMPC)Mbp HET Early adult 0.00
cystolithiasis Afdnem1(IMPC)Mbp HET Late adult 0.00
small heart Afdnem1(IMPC)Mbp HET Late adult 0.00
preweaning lethality, complete penetrance Afdnem1(IMPC)Mbp HOM   Early adult 0.00
abnormal kidney morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal spleen morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal lymph node morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal urinary bladder morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
enlarged liver Afdnem1(IMPC)Mbp HET Late adult 0.00
enlarged kidney Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal liver morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal spleen morphology Afdnem1(IMPC)Mbp HET Early adult 0.00
abnormal skin morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
enlarged spleen Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal neural tube closure Afdnem1(IMPC)Mbp HET E9.5 0.00
abnormal gallbladder morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal heart morphology Afdnem1(IMPC)Mbp HET Late adult 0.00
abnormal hindbrain development Afdnem1(IMPC)Mbp HET E9.5 0.00
decreased freezing behavior Afdnem1(IMPC)Mbp HET   Early adult 7.27×10-05

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
20 Images
X-ray: XRay Images Whole Body Dorso Ventral
60 Images
X-ray: XRay Images Whole Body Dorso Ventral
30 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Afdnem1(IMPC)Mbp Exon Deletion Mice, Tissue
Afdntm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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