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Gene: Cyp2c38 MGI:1306819

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Gene Summary

Name:
cytochrome P450, family 2, subfamily c, polypeptide 38
Synonyms:
N/A

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal bone structure Cyp2c38em1(IMPC)Bay HET Early adult 9.22×10-20
increased bone mineral content Cyp2c38em1(IMPC)Bay HET Early adult 2.71×10-18
decreased body length Cyp2c38em1(IMPC)Bay HET Early adult 5.05×10-13
preweaning lethality, complete penetrance Cyp2c38em1(IMPC)Bay HOM   Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Cyp2c38 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Cyp2c38 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Coumarin Resistance
OMIM:122700

The table below shows human diseases predicted to be associated to Cyp2c38 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Melorheostosis, Isolated
Hyperostosis, Increased bone mineral density OMIM:155950
Coumarin Resistance
OMIM:122700

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Cyp2c38

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cyp2c38.

No publications found that use IMPC mice or data for Cyp2c38.

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MGI Allele Allele Type Produced
Cyp2c38em1(IMPC)Bay Exon Deletion Mice

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