Gene: Zfp239

Name
zinc finger protein 239
MGI ID
MGI:1306812
Synonyms
Mok2 Mok-2
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (520) Expression & images (45) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector gd cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_034_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_026_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of B220+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Kyphosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Lumbar processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Indirect Calorimetry / Total food intake HOM 0f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CAL_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Fibula HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.672 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Shape of vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - % of gd T cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of DC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of mature NK cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / LDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0118 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_018_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Zygomatic bone HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Calcium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0592 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Shape of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Macrophages - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_IPG_012_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_003_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Potassium HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.732 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Myeloid cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0249 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Phosphorus HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.923 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Viability Primary Screen / Outcome HOM 27f:31m Supplied as data Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of DC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CAL_017_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / B1a cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Triglycerides HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0142 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Platelet count HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_009_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_033_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_025_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_010_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 2f:2m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Scoliosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_019_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Fusion of vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Tibia HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_004_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of gd T cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_011_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Sodium HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.212 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / HDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.377 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Granulocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of NK cellls HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of NK cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Caudal processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total B2 cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of ribs right HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_008_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Alpha-amylase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.125 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Iron HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.253 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of Treg HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Magnesium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.939 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_036_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 2f:2m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of NK cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of Treg HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI DSS Histology / Pre-Day 10 Death HOM 2f:2m - 1.00 FAILED - Not enough mutant or control data
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Femur HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_040_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Free fatty acids HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0125 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 0.522 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.290 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_020_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of B220+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Red blood cell count HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of lymphocytes HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_012_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Thoracic processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Humerus HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_027_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Total B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.593 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Lordosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Ulna HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Sacral processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of Treg HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'IMPC_XRY_017_001' control subset (Female - 20, Male - 3) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_007_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of ribs left HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_035_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 2f:2m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of B220+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_013_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Glucose HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.145 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Skull shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 2f:2m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Chloride HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.202 Success
Zfp239tm1b(KOMP)Wtsi WTSI Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.628 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of lymphocytes HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_028_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Monocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Shape of ribcage HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / White blood cell count HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_001_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Alanine aminotransferase HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.902 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Eosinophils - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Creatinine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.128 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / B1a cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Radius HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Mean platelet volume HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_019_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_006_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Brachydactyly HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of gd T cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Scapulae HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_022_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of lymphocytes HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Polysyndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Hematocrit HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Creatine kinase HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.293 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_038_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_029_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of B220+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_031_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Thyroxine HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.434 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Indirect Calorimetry / Total water intake HOM 0f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CAL_021_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of NK cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.672 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_014_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Clavicle HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of GC cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Digit integrity HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Total protein HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.861 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector gd T cells - % of gd T cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_037_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_005_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Aspartate aminotransferase HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.453 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of NK cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of lymphocytes HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Hemoglobin HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_021_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Syndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of lymphocytes HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Glycerol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.864 Success
Zfp239tm1b(KOMP)Wtsi WTSI Heart Weight / Heart weight HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HWT_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 7f:7m Fisher Exact Test framework 0.0101 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of B220+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_032_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_015_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Cervical processes HOM 7f:7m Fisher Exact Test framework 0.137 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Monocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_024_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Plasma cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:0m Mixed Model framework, generalized least squares, equation withoutWeight 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:0m Mixed Model framework, generalized least squares, equation withoutWeight 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Total cholesterol HOM 7f:7m Mixed Model framework, generalized least squares, equation withWeight 0.00639 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_016_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Albumin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.131 Success
Zfp239tm1b(KOMP)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_IPG_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Transitional vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Pelvis HOM 7f:7m Fisher Exact Test framework 0.522 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total ab T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Shape of spine HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Mean cell volume HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Macrophages - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of GC cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Mandibles HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of immature NK cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of Treg HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Granulocytes - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Number of digits HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Zfp239tm1b(KOMP)Wtsi WTSI Trichuris / Presence of worms in caecum HOM 6f:0m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 7f:0m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 0f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_001_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI DSS Histology / Average histology score HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_017_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Fructosamine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.347 Success
Zfp239tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 0f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 7f:0m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Alkaline phosphatase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.224 Success
Zfp239tm1b(KOMP)Wtsi WTSI Trichuris / Pre day 32 death HOM 6f:0m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Teeth HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_023_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 2f:2m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_IPG_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Clinical Chemistry / Total bilirubin HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.218 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of DC HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Fusion of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_039_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_030_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Joints HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI X-ray / Fusion of processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Hematology / Red blood cell distribution width HOM 7f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_027_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_002_001' control subset (Female - 41, Male - 7) to allow the application of RR plus framework.
Zfp239tm1b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 2f:2m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of B220+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Zfp239tm1b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
42 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Forepaw
14 Images
Anti-nuclear antibody assay
10 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Zfp239tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Zfp239tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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