Genes Phenotypes

Gene: Pip5k1c

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Name
phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
MGI ID
MGI:1298224
Synonyms
PIP5KIgamma
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (107) All data table (528)
Expression & images (80) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
persistence of hyaloid vascular system Pip5k1ctm1b(KOMP)Wtsi HET Early adult 9.81×10-06
preweaning lethality, complete penetrance Pip5k1ctm1b(KOMP)Wtsi HOM Early adult 0.00
edema Pip5k1ctm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal embryo size Pip5k1ctm1b(KOMP)Wtsi HET E12.5 0.00
embryonic growth retardation Pip5k1ctm1b(KOMP)Wtsi HET E12.5 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (2/4)  Section images
Aorta 4 No  (2/4)  Section images
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 4 No  (4/4)  Section images
Brainstem 4 No  (2/4)  Section images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (2/4)  Section images
Cerebellum 4 No  (2/4)  Section images
Cerebral cortex 4 No  (2/4)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 4 No  (2/4)  Section images
Gall bladder 2 No N/A
Heart 4 No  (3/4)  Section images
Hippocampus 4 No  (2/4)  Section images
Hypothalamus 4 No  (2/4)  Section images
Kidney 4 No  (18/584)  (4/4)  Section images
Large intestine 4 No  (10/584)  (3/4)  Section images
Liver 4 No  (2/4)  Section images
Lower urinary tract 4 No  (2/4) N/A
Lung 4 No  (2/4)  Section images
Lymph node 4 No  (4/4)  Section images
Mammary gland 4 No  (1/4)  Section images
Midbrain 2 No  (2/2)  Section images
Esophagus 2 No N/A
Olfactory lobe 4 No  (2/4)  Section images
Ovary 4 No  (1/584)  (1/4)  Section images
Oviduct 4 No  (2/4)  Section images
Pancreas 4 No  (5/584)  (3/4)  Section images
Parathyroid gland 2 No N/A
Peripheral nervous system 4 No  (4/4)  Section images
Peyer's patch 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 4 No  (4/4)  Section images
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skeletal muscle tissue 2 No N/A
Skin 4 No  (2/4)  Section images
Small intestine 4 No  (9/584)  (3/4)  Section images
Spinal cord 4 No  (4/4)  Section images
Spleen 4 No  (2/584)  (3/4)  Section images
Stomach 4 No  (12/584)  (2/4)  Section images
Striatum 4 No  (2/4)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 4 No  (2/584)  (2/4)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 4 No  (3/4)  Section images
Thyroid gland 4 No  (15/584)  (2/4)  Section images
Trachea 4 No  (2/4)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 4 No  (2/4)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 4 No  (2/4)  Section images
LacZ Wholemount Images
LacZ Section Images
adipose tissue (1)
White Adipose Tissue expression
MA:0000058
cardiovascular system (3)
Aorta expression
MA:0000062
digestive system (7)
Esophagus expression
MA:0000352
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Mammary gland expression
MA:0000145
immune system (4)
Lymph Node expression
MA:0000139
integumental system (2)
Mammary gland expression
MA:0000145
musculoskeletal system (1)
Skeletal Muscle expression
MA:0003148
nervous system (13)
Brain expression
MA:0000168
postnatal mouse (44)
Adrenal gland expression
MA:0000116
reproductive system (5)
Epididymis expression
MA:0000397
respiratory system (3)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
MA:0000104
trunk (22)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
Pip5k1ctm1a(KOMP)Wtsi
heart, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
uterus, oviduct, ovary, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
kidney, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
thymus, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
brain, HET, Female, WTSI

View all 15 images

Pip5k1ctm1a(KOMP)Wtsi
heart, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
uterus, oviduct, ovary, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
kidney, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
thymus, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI

View all 11 images

Pip5k1ctm1a(KOMP)Wtsi
thymus, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
mesenteric lymph node, lymph node, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
spleen, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
peyer's patch, small intestine, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
brain, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
brain, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
pituitary gland, peripheral nervous system, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
spinal cord, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
peyer's patch, small intestine, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
large intestine, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
uterus, oviduct, ovary, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
testis, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
kidney, HET, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
heart, HET, Male, WTSI
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (2/3) N/A
Dorsal root ganglion 2  (1/57) Image Only N/A
Ear 2  (1/504) Image Only N/A
Embryo 2  (1/505)  (2/3)  Wholemount images
Eye 2  (1/504)  (2/3) N/A
Foot 2  (1/504)  (2/3) N/A
Forebrain 2  (1/504)  (2/3) N/A
Forelimb 2  (1/504)  (2/3) N/A
Fronto-nasal process 2  (1/58) Image Only N/A
Hand 2  (1/503)  (2/3) N/A
Head 2  (5/504)  (2/3) N/A
Heart 2  (1/504)  (2/3) N/A
Hindbrain 2  (6/504)  (2/3) N/A
Hindlimb 2  (1/503)  (2/3) N/A
Liver 2  (1/504) Image Only N/A
Lung 2  (1/500) Image Only N/A
Mandibular process 2  (1/504)  (2/3) N/A
Maxillary process 2  (1/504)  (2/3) N/A
Midbrain 2  (1/504)  (2/3) N/A
Nose 2  (1/70)  (2/3) N/A
Oral cavity 2  (1/504) Image Only N/A
Skin 2  (1/504)  (2/3) N/A
Spinal cord 2  (1/69)  (2/3) N/A
Tail 2  (1/504)  (2/3) N/A
Tail somite 2  (1/504) Image Only N/A
embryo or Unassigned (12)
Embryo imageOnly
EMAPA:16039 embryo

 Associated Images

Gross Morphology Embryo E18.5
4 Images
Original Image
Adult LacZ: LacZ Images Section
44 Images
X-ray: XRay Images Forepaw
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
Legacy Phenotype Associated Images
Pip5k1ctm1a(KOMP)Wtsi
body, WT, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
head, WT, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
body, WT, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
head, WT, Male, WTSI
Pip5k1ctm1a(KOMP)Wtsi
body, WT, Male, WTSI

View all 177 images

Pip5k1ctm1a(KOMP)Wtsi
eye, abnormal placement of pupils, abnormal pupil morphology, HET, Female, WTSI
Pip5k1ctm1a(KOMP)Wtsi
back skin, HET, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pip5k1ctm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pip5k1ctm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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