Gene: Tbc1d22a

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Name
TBC1 domain family, member 22a
MGI ID
MGI:1289265
Synonyms
D15Ertd781e
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alanine transaminase level Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 1.55×10-14
increased circulating free fatty acids level Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 2.20×10-07
thrombocytopenia Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 2.69×10-05
decreased circulating fructosamine level Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 1.93×10-05
increased circulating amylase level Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 6.07×10-15
increased circulating aspartate transaminase level Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 4.17×10-09
increased mean platelet volume Tbc1d22atm1b(KOMP)Wtsi HOM   Early adult 7.98×10-05
increased red blood cell distribution width Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 6.72×10-10
increased circulating alkaline phosphatase level Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 1.38×10-13
decreased circulating triglyceride level Tbc1d22atm1b(KOMP)Wtsi HOM Early adult 6.73×10-09
decreased circulating glucose level Tbc1d22atm1b(KOMP)Wtsi HOM   Early adult 4.41×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (2/2) N/A
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583) N/A
2 No  (1/176) N/A
2 No  (1/583)  (2/2) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583) N/A
2 No  (6/583)  (1/2) N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No N/A
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
14 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
Eye Morphology: Images Slit Lamp
1 Images
Legacy Phenotype Associated Images

View all 70 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tbc1d22atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tbc1d22atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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