Tbc1d22a | TBC1 domain family, member 22a
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system
16 No significant impact
6 Not tested
Data collections
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
increased circulating amylase level | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 5.33x10-12 | ||
decreased circulating fructosamine level | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 2.16x10-6 | ||
thrombocytopenia | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 1.94x10-5 | ||
increased circulating aspartate transaminase level | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 3.05x10-19 | ||
increased circulating alanine transaminase level | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 9.95x10-34 | ||
increased circulating creatinine level | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 4.88x10-5 | ||
increased circulating free fatty acids level | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 1.54x10-6 | ||
increased mean platelet volume | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 2.66x10-6 | ||
increased red blood cell distribution width | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 7.08x10-6 | ||
increased circulating alkaline phosphatase level | 1 supporting dataset | Tbc1d22atm1b(KOMP)Wtsi | homozygote | Early adult | 2.62x10-53 |
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External links
No external links available for Tbc1d22a.
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Tbc1d22atm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Tbc1d22atm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Tbc1d22atm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |