Gene: Setd3

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Name
SET domain containing 3
MGI ID
MGI:1289184
Synonyms
2610305M23Rik D12Ertd771e 2610102I01Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased lymphocyte cell number Setd3tm1.1(NCOM)Mfgc HOM Early adult 6.48×10-06
decreased body length Setd3tm1.1(NCOM)Mfgc HOM Early adult 2.35×10-05
decreased prepulse inhibition Setd3tm1.1(NCOM)Mfgc HOM Early adult 6.00×10-12
cardiovascular system phenotype Setd3tm1.1(NCOM)Mfgc HOM   Early adult 4.84×10-05
hydrometra Setd3tm1.1(NCOM)Mfgc HOM Early adult 0.00
increased bone mineral density Setd3tm1.1(NCOM)Mfgc HOM Early adult 9.76×10-07
decreased mean platelet volume Setd3tm1.1(NCOM)Mfgc HOM Early adult 5.85×10-05
small testis Setd3tm1.1(NCOM)Mfgc HOM Early adult 0.00
short tibia Setd3tm1.1(NCOM)Mfgc HOM Early adult 6.67×10-10
increased circulating alkaline phosphatase level Setd3tm1.1(NCOM)Mfgc HOM Early adult 3.85×10-05
increased leukocyte cell number Setd3tm1.1(NCOM)Mfgc HOM   Early adult 4.13×10-06
abnormal pancreas morphology Setd3tm1.1(NCOM)Mfgc HOM Early adult 0.00
abnormal seminal vesicle morphology Setd3tm1.1(NCOM)Mfgc HOM Early adult 0.00
increased bone mineral content Setd3tm1.1(NCOM)Mfgc HOM Early adult 3.20×10-06
vertebral fusion Setd3tm1.1(NCOM)Mfgc HOM   Early adult 6.83×10-07

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
16 Images
Gross Pathology and Tissue Collection
7 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
X-ray: XRay Images Skull Lateral Orientation
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
16 Images
Histopathology
13 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
Combined SHIRPA and Dysmorphology
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Brain - MPATH diagnostic term hydrocephalus Setd3tm1.1(NCOM)Mfgc HOM Early adult
Skeletal muscle - developmental and structural abnormality Setd3tm1.1(NCOM)Mfgc HOM Early adult
Brain - process of degenerative change Setd3tm1.1(NCOM)Mfgc HOM Early adult

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MGI Allele Allele Type Produced
Setd3tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Setd3tm1.1(NCOM)Mfgc Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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