Gene: Mpzl2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
thick ventricular wall Mpzl2tm1b(EUCOMM)Hmgu HET Early adult 7.09×10-06
decreased startle reflex Mpzl2tm1b(EUCOMM)Hmgu HOM Early adult 5.56×10-05
abnormal coat/hair pigmentation Mpzl2tm1b(EUCOMM)Hmgu HOM Early adult 3.15×10-05
increased exploration in new environment Mpzl2tm1b(EUCOMM)Hmgu HOM Early adult 3.64×10-06
long tibia Mpzl2tm1b(EUCOMM)Hmgu HET Early adult 4.04×10-10
abnormal ear morphology Mpzl2tm1b(EUCOMM)Hmgu HOM Early adult 6.27×10-05
abnormal gait Mpzl2tm1b(EUCOMM)Hmgu HOM Early adult 5.09×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583)  (2/2)  Wholemount images
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (1/2)  Wholemount images
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505) N/A
2  (1/505) N/A
2  (1/506)  (2/4) N/A
2  (1/505) N/A
2  (1/505)  (2/4) N/A
2  (1/505) N/A
2  (1/505)  (1/4) N/A
2  (1/505)  (2/4) N/A
2  (5/505)  (2/4) N/A
2  (1/505) Image Only N/A
2  (6/505) N/A
2  (1/505)  (1/4) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A

 Associated Images

Echo: M-Mode Images
116 Images
X-ray: XRay Images Whole Body Lateral Orientation
3 Images
X-ray: XRay Images Whole Body Dorso Ventral
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
6 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mpzl2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Mpzl2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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