Gene: Epc2

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Name
enhancer of polycomb homolog 2
MGI ID
MGI:1278321
Synonyms
D2Ertd694e
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (5)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased thigmotaxis Epc2tm1b(EUCOMM)Wtsi HET Early adult 9.44×10-06
decreased body weight Epc2tm1e(EUCOMM)Wtsi HET Early adult 3.15×10-14
abnormal eye morphology Epc2tm1a(EUCOMM)Wtsi HOM   Early adult 3.18×10-06
abnormal behavior Epc2tm1b(EUCOMM)Wtsi HET Early adult 9.44×10-06
abnormal lens morphology Epc2tm1b(EUCOMM)Wtsi HET Early adult 1.38×10-06
increased circulating alkaline phosphatase level Epc2tm1a(EUCOMM)Wtsi HOM Early adult 2.55×10-06
increased respiratory quotient Epc2tm1b(EUCOMM)Wtsi HET   Early adult 2.75×10-05
decreased lactate dehydrogenase level Epc2tm1a(EUCOMM)Wtsi HOM Early adult 1.20×10-05
increased anxiety-related response Epc2tm1b(EUCOMM)Wtsi HET Early adult 7.52×10-05
abnormal vertebral arch morphology Epc2tm1e(EUCOMM)Wtsi HET Early adult 4.47×10-05
thrombocytopenia Epc2tm1a(EUCOMM)Wtsi HOM Early adult 2.20×10-05
hypoactivity Epc2tm1b(EUCOMM)Wtsi HET Early adult 1.14×10-06
abnormal retinal pigmentation Epc2tm1a(EUCOMM)Wtsi HOM   Early adult 4.95×10-05
cataract Epc2tm1b(EUCOMM)Wtsi HET Early adult 5.99×10-07
preweaning lethality, complete penetrance Epc2tm1b(EUCOMM)Wtsi HOM   Early adult 7.56×10-08
decreased total retina thickness Epc2tm1b(EUCOMM)Wtsi HET   Early adult 4.14×10-05
hyperactivity Epc2tm1b(EUCOMM)Wtsi HET Early adult 8.34×10-07

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Legacy Phenotype Associated Images

View all 189 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Epc2tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Epc2tm34341(L1L2_Bact_P) Targeting vectors
Epc2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Epc2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Epc2tm1e(EUCOMM)Wtsi Targeted, non-conditional allele Mice

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