The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Sap18 by phenotypic similarity.
|Attention Deficit-Hyperactivity Disorder 8||
||Attention deficit hyperactivity disorder||OMIM:619957|
|Attention Deficit-Hyperactivity Disorder||
||Hyperactivity, Attention deficit hyperactivity disorder||OMIM:143465|
|Intellectual Developmental Disorder, Autosomal Recessive 54||
|22q13 deletion syndrome (Phelan-Mcdermid syndrome)||
|Potocki-Lupski syndrome (17p11.2 duplication syndrome)||
|Intellectual Developmental Disorder, X-Linked 77||
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|MGI Allele||Allele Type||Produced|
|Sap18tm1(KOMP)Vlcg||Reporter-tagged deletion allele (with selection cassette)||ES Cells|