Gene: Dlg4

Name
discs large MAGUK scaffold protein 4
MGI ID
MGI:1277959
Synonyms
PSD-95 SAP90A SAP90 PSD95 Dlgh4
View
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased NK cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased T cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
increased lean body mass Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 2.13×10-10
decreased lean body mass Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 6.28×10-05
decreased neutrophil cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
hypoactivity Dlg4tm1Grnt HOM postnatal 7.29×10-07
decreased Ly6C high monocyte number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased total body fat amount Dlg4tm1Grnt HOM postnatal 7.11×10-06
increased circulating sodium level Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 3.74×10-09
decreased effector memory CD8-positive, alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 6.04×10-05
decreased Ly6C low monocyte number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased monocyte cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
increased B cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased NK T cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 3.60×10-06
increased circulating phosphate level Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 8.56×10-06
decreased exploration in new environment Dlg4tm1Grnt HOM postnatal 2.41×10-20
decreased circulating HDL cholesterol level Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 2.24×10-10
increased bone mineral content Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 3.84×10-07
decreased circulating LDL cholesterol level Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 9.70×10-06
decreased CD4-positive, alpha beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
abnormal behavior Dlg4tm1Grnt HOM postnatal 1.92×10-07
decreased grip strength Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 5.65×10-12
decreased bone mineral content Dlg4tm1Grnt HOM postnatal 4.88×10-06
decreased alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased CD8-positive, alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased eosinophil cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased effector memory CD4-positive, alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 0.00
decreased body weight Dlg4tm1Grnt HOM postnatal 1.40×10-24
decreased total body fat amount Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 9.35×10-15
tremors Dlg4tm1e(EUCOMM)Wtsi HOM postnatal 1.68×10-08

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
25 Images
X-ray: XRay Images Dorso Ventral
30 Images
Eye Morphology: Images Slit Lamp
2 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Lateral Orientation
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Anti-nuclear antibody assay
7 Images
DSS Histology
8 Images
Legacy Phenotype Associated Images

View all 40 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Dlg4tm1e(EUCOMM)Wtsi Targeted, non-conditional allele Mice
Dlg4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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