Gene: Dlg4

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Name
discs large MAGUK scaffold protein 4
MGI ID
MGI:1277959
Synonyms
PSD95 Dlgh4 SAP90A PSD-95 SAP90
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased grip strength Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 5.18×10-12
decreased eosinophil cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased monocyte cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased effector memory CD8-positive, alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 6.65×10-05
decreased Ly6C low monocyte number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased CD8-positive, alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
increased circulating phosphate level Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 8.14×10-05
decreased CD4-positive, alpha beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased lean body mass Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 5.33×10-05
increased mean corpuscular volume Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 8.27×10-05
decreased Ly6C high monocyte number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased NK cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased NK T cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 3.80×10-06
abnormal behavior Dlg4tm1Grnt HOM Early adult 1.92×10-07
hypoactivity Dlg4tm1Grnt HOM Early adult 7.29×10-07
decreased exploration in new environment Dlg4tm1Grnt HOM Early adult 2.41×10-20
decreased body length Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 8.72×10-05
decreased neutrophil cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased total body fat amount Dlg4tm1Grnt HOM Early adult 7.11×10-06
decreased alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
increased circulating sodium level Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 1.85×10-09
decreased T cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
increased B cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased circulating HDL cholesterol level Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 6.63×10-11
increased bone mineral content Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 4.38×10-07
tremors Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 1.04×10-08
decreased effector memory CD4-positive, alpha-beta T cell number Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 0.00
decreased total body fat amount Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 9.35×10-15
decreased circulating LDL cholesterol level Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 5.41×10-06
decreased bone mineral content Dlg4tm1Grnt HOM Early adult 4.88×10-06
decreased body weight Dlg4tm1Grnt HOM Early adult 1.40×10-24
increased lean body mass Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 2.66×10-10
increased circulating chloride level Dlg4tm1e(EUCOMM)Wtsi HOM Early adult 3.46×10-05

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 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
30 Images
X-ray: XRay Images Whole Body Lateral Orientation
23 Images
X-ray: XRay Images Forepaw
10 Images
Anti-nuclear antibody assay
7 Images
Eye Morphology: Images Slit Lamp
2 Images
Legacy Phenotype Associated Images

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 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Dlg4tm1e(EUCOMM)Wtsi Targeted, non-conditional allele Mice
Dlg4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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