Gene: Ncoa1

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Name
nuclear receptor coactivator 1
MGI ID
MGI:1276523
Synonyms
SRC1 KAT13A SRC-1 bHLHe74 steroid receptor coactivator-1 SRC-a/NCoA-1
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 1.62×10-07
decreased circulating cholesterol level Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 1.37×10-05
hyperactivity Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 7.07×10-07
decreased circulating glucose level Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 3.12×10-06
increased bone mineral content Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 1.23×10-11
decreased total body fat amount Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 1.87×10-06
increased lean body mass Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 6.31×10-07
abnormal behavior Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 1.02×10-07
decreased fasting circulating glucose level Ncoa1tm1.1(KOMP)Vlcg HOM Early adult 9.65×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (1/2)  Section images
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (1/2)  Section images
Harderian gland 2 No  (2/2)  Section images
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No  (1/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No  (1/2)  Section images
Mesenteric lymph node 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Parathyroid gland 2 No N/A
Parotid gland 2 No  (2/2)  Section images
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Section images
Prostate gland 2 No  (12/584)  (1/2)  Section images
Quadriceps 2 No  (2/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (1/2)  Section images
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (2/2)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2)  Section images
Tongue 2 No  (5/127)  (2/2)  Section images
Trachea 2 No  (2/2)  Section images
Trigeminal V nerve 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
127 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ncoa1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Ncoa1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Ncoa1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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