Gene: Axin2

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Phenotype System Allele Zyg Sex Life Stage P Value
abnormal craniofacial morphology Axin2tm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal head size Axin2tm1b(KOMP)Wtsi HET E18.5 0.00
abnormal skin coloration Axin2tm1b(KOMP)Wtsi HET Early adult 1.62×10-10
abnormal limb morphology Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal vibrissa morphology Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal vibrissa morphology Axin2tm1b(KOMP)Wtsi HET E18.5 0.00
abnormal head size Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal auditory brainstem response Axin2tm1b(KOMP)Wtsi HET Early adult 6.08×10-05
abnormal embryo size Axin2tm1b(KOMP)Wtsi HET E18.5 0.00
abnormal pericardium morphology Axin2tm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal facial morphology Axin2tm1b(KOMP)Wtsi HET E18.5 0.00
abnormal embryo size Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal head shape Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal outer ear morphology Axin2tm1b(KOMP)Wtsi HET E18.5 0.00
abnormal body wall morphology Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal outer ear morphology Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00
preweaning lethality, complete penetrance Axin2tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal heart morphology Axin2tm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal head shape Axin2tm1b(KOMP)Wtsi HET E18.5 0.00
abnormal facial morphology Axin2tm1b(KOMP)Wtsi HOM E18.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (2/2)  Wholemount images
Aorta 2 No  (1/589)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (3/589)  (2/2)  Wholemount images
Brainstem 2 No  (2/589)  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (3/589)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/589)  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (1/589)  (2/2)  Wholemount images
Hippocampus 2 No  (3/589)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/589)  (2/2)  Wholemount images
Kidney 2 No  (20/589)  (2/2)  Wholemount images
Large intestine 2 No  (10/589)  (2/2)  Wholemount images
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No  (1/589)  (2/2)  Wholemount images
Lung 2 No  (1/589)  (2/2)  Wholemount images
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2)  Wholemount images
Mesenteric lymph node 2 No  (2/2)  Wholemount images
Olfactory lobe 2 No  (2/589)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/589)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/589)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/589)  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (1/589)  (1/2)  Wholemount images
Prostate gland 2 No  (12/589)  (1/2)  Wholemount images
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/589)  (2/2)  Wholemount images
Spinal cord 2 No  (2/589)  (2/2)  Wholemount images
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589)  (2/2)  Wholemount images
Striatum 2 No  (3/589)  (2/2)  Wholemount images
Testis 2 No  (5/589)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (16/589)  (2/2)  Wholemount images
Trachea 2 No  (2/589)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/388)  (1/2)  Wholemount images
Vascular system 2 No  Wholemount images
White adipose tissue 2 No  (2/2)  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/61)  (2/2) N/A
Axial skeleton 2  (1/65)  (2/2) N/A
Brain 2  (6/506)  (2/2) N/A
Central nervous system ganglion 2  (1/74)  (2/2) N/A
Cranium 2  (1/65)  (2/2) N/A
Dorsal root ganglion 2  (1/61)  (2/2) N/A
Ear 2  (1/506)  (2/2) N/A
Embryo 2  (1/507)  (2/2) N/A
Outer ear 2  (1/70)  (2/2) N/A
Eye 2  (1/506)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/56)  (2/2) N/A
Foot 2  (1/506)  (2/2) N/A
Forearm 2  (1/301)  (2/2) N/A
Forebrain 2  (1/506)  (2/2) N/A
Forelimb 2  (1/506)  (2/2) N/A
Fronto-nasal process 2  (1/62)  (2/2) N/A
Gut 2  (1/60)  (2/2) N/A
Hand 2  (1/505)  (2/2) N/A
Head 2  (5/506)  (2/2) N/A
Head mesenchyme 2  (1/61)  (2/2) N/A
Heart 2  (1/506)  (2/2) N/A
Heart ventricle 2  (1/61)  (2/2) N/A
Hindbrain 2  (6/506)  (2/2) N/A
Hindlimb 2  (1/505)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/65)  (2/2) N/A
Inner ear 2  (1/65)  (2/2) N/A
Intestine 2  (1/59)  (2/2) N/A
Liver 2  (1/506)  (2/2) N/A
Lower leg 2  (1/301)  (2/2) N/A
Lung 2  (1/502)  (2/2) N/A
Mandibular process 2  (1/506)  (2/2) N/A
Maxillary process 2  (1/506)  (2/2) N/A
Mesonephros of female 2  (1/56)  (1/2) N/A
Mesonephros of male 2  (1/56)  (1/2) N/A
Metanephros 2  (1/56)  (2/2) N/A
Midbrain 2  (1/506)  (2/2) N/A
Nasal septum 2  (1/61)  (2/2) N/A
Nose 2  (1/74)  (2/2) N/A
Notochord 2  (1/61)  (2/2) N/A
Oral cavity 2  (1/506)  (2/2) N/A
Outflow tract 2  (1/61)  (2/2) N/A
Pancreas 2  (1/56)  (2/2) N/A
Pericardium 2  (1/56)  (2/2) N/A
Pharynx 2  (1/56)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/65)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/58)  (2/2) N/A
Skeleton 2  (1/74)  (2/2) N/A
Skin 2  (1/506)  (2/2) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Stomach 2  (1/56)  (2/2) N/A
Tail 2  (1/506)  (2/2) N/A
Tail somite 2  (1/506)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/56)  (2/2) N/A
Tongue 2  (1/56)  (2/2) N/A
Trachea 2  (1/60)  (2/2) N/A
Trunk mesenchyme 2  (1/61)  (2/2) N/A
Umbilical artery embryonic part 2  (1/61)  (2/2) N/A
Umbilical vein embryonic part 2  (1/61)  (2/2) N/A
Upper arm 2  (1/301)  (2/2) N/A
Upper leg 2  (1/301)  (2/2) N/A
Urinary system 2  (1/60)  (2/2) N/A
Vibrissa 2  (1/70)  (2/2) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Forepaw
9 Images
Adult LacZ: LacZ Images Wholemount
78 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

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MGI Allele Allele Type Produced
Axin2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Axin2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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