Gene: Il12rb2

Name
interleukin 12 receptor, beta 2
MGI ID
MGI:1270861
Synonyms
Ifnm IL-12RB2 A930027I18Rik
View
N/A
Other links
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Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alanine aminotransferase HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.833 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.124 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Triglycerides HOM 7f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00479 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.545 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / N1-N3 Interval (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Percentage center time HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00707 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 3f:2m 0.173 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.975 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / P1-N1 amplitude (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Periphery distance travelled HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.285 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0320 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep light phase percent HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.131 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Tail Suspension / Latency to immobility HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.487 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Calcium HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0957 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 0.0126 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0518 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.358 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.316 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / N1 Latency (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Rotarod / Learning slope HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.804 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Potassium HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00485 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.118 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.882 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 3f:2m 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Phosphorus HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.402 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Viability Primary Screen / Outcome HOM 47f:43m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths mean HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0970 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.127 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Center distance travelled HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.296 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 3f:2m 0.329 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.822 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Triglycerides HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.279 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 3f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 5f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_ECT_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0889 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.689 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.341 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total protein HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.256 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Plasma Chemistry / HDL cholesterol HOM 7f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0360 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.639 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.138 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep standard deviation HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.332 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Aspartate aminotransferase HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.221 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / Preyer Reflex HOM 1f:1m - 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Tail Suspension / Time immobile HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.601 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.555 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / P3-N3 amplitude (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.129 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Whole arena resting time HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.923 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.157 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.509 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / P1 Latency (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Center average speed HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0858 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Sodium HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00219 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep dark phase percent HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.922 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Heart Weight / Heart weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.200 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000942 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / HDL-cholesterol HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0180 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.448 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / P1-P3 Interval (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0586 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Latency to first transition into dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0275 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.498 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.181 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Periphery average speed HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.837 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.873 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in light HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.822 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Total cholesterol HOM 7f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.116 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.409 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0851 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Distance travelled - total HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.513 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths mean HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.464 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.810 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / Click-evoked ABR threshold HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Iron HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.455 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 3f:2m 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total cholesterol HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00348 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0320 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Periphery permanence time HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00704 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Albumin HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.645 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.135 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.802 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / Click +20dB waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.273 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / Mean cell volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.528 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep daily percent HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.368 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Free fatty acids HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.437 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Center permanence time HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00707 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 3f:2m 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000354 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00450 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0848 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.523 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep mean HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00257 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.262 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00582 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / N3 Latency (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths mean HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.738 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 0.391 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Rotarod / Average duration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0735 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Glucose HOM 7f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.187 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.154 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / Click +50dB waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 0.197 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.265 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alkaline phosphatase HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0423 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hole-board Exploration / Total holepokes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.172 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Number of rears - total HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.773 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0618 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0952 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / Click-evoked ABR waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.286 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.412 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total bilirubin HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.207 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.318 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.204 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Peak wake with respect to dark onset median HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.974 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Glucose HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0119 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0972 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / P3 Latency (at each stimulus level) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Tail Suspension / Climbing HOM 8f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.957 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00152 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Chloride HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.647 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Free fatty acids HOM 7f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000828 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Rotarod / Learning difference HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.866 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.264 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0983 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR waveforms (numerical format) HOM 1f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 0.317 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Open Field / Whole arena average speed HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.513 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths standard deviation HOM 5f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.175 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Il12rb2tm1.1(KOMP)Vlcg JAX Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0377 Success
Il12rb2tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (1/2) N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584) N/A
Thalamus 2 No N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Sleep Wake: Wake state (bmp file)
9 Images
X-ray: XRay Images Forepaw
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Lateral Orientation
11 Images
Combined SHIRPA and Dysmorphology
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Il12rb2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Il12rb2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Il12rb2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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