Genes Phenotypes

Gene: Gck

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Name
glucokinase
MGI ID
MGI:1270854
Synonyms
hexokinase 4 HK4 Hlb62 MODY2 Gls006
Viability
Homozygous - Subviable
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3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (196) All data table (200)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating fructosamine level Gckem1(IMPC)H HET postnatal 1.19×10-10
impaired glucose tolerance Gckem1(IMPC)H HET postnatal 7.26×10-29
increased circulating glucose level Gckem1(IMPC)H HET postnatal 2.02×10-17
increased fasted circulating glucose level Gckem1(IMPC)H HET postnatal 2.77×10-11
increased circulating alkaline phosphatase level Gckem1(IMPC)H HET postnatal 1.12×10-05
preweaning lethality, incomplete penetrance Gckem1(IMPC)H HOM n/a 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Gckem1(IMPC)H Exon Deletion Mice
Gcktm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells