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Genes Phenotypes

Gene: Gck

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Name
glucokinase
MGI ID
MGI:1270854
Synonyms
HK4 MODY2 hexokinase 4 Gls006 Hlb62
Viability
Homozygous - Subviable
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3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (190) All data table (344)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Gckem1(IMPC)H HET Early adult 4.77×10-09
increased circulating fructosamine level Gckem1(IMPC)H HET Early adult 2.53×10-09
preweaning lethality, incomplete penetrance Gckem1(IMPC)H HOM   Early adult 0.00
increased fasting circulating glucose level Gckem1(IMPC)H HET Early adult 1.25×10-09
impaired glucose tolerance Gckem1(IMPC)H HET Early adult 8.88×10-15
increased circulating glucose level Gckem1(IMPC)H HET Early adult 2.33×10-14

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 Expression

Expression data not available

 Associated Images

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X-ray: XRay Images Whole Body Dorso Ventral
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X-ray: XRay Images Whole Body Lateral Orientation
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 Disease Models

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MGI Allele Allele Type Produced
Gckem1(IMPC)H Exon Deletion Mice
Gcktm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells