Genes Phenotypes

Gene: Gck

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Name
glucokinase
MGI ID
MGI:1270854
Synonyms
HK4 hexokinase 4 MODY2 Hlb62 Gls006
Viability
Homozygous - Subviable
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (197) All data table (314)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
impaired glucose tolerance Gckem1(IMPC)H HET Early adult 5.16×10-27
increased circulating glucose level Gckem1(IMPC)H HET Early adult 5.41×10-17
increased fasting circulating glucose level Gckem1(IMPC)H HET Early adult 2.30×10-11
increased circulating fructosamine level Gckem1(IMPC)H HET Early adult 1.04×10-10
increased circulating alkaline phosphatase level Gckem1(IMPC)H HET Early adult 1.14×10-05
preweaning lethality, incomplete penetrance Gckem1(IMPC)H HOM Early adult 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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MGI Allele Allele Type Produced
Gckem1(IMPC)H Exon Deletion Mice
Gcktm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells