Gene: Pik3c2a

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Name
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
MGI ID
MGI:1203729
Synonyms
PI3KC2
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Pik3c2atm1b(EUCOMM)Hmgu HOM E9.5 0.00
enlarged lymph nodes Pik3c2atm1b(EUCOMM)Hmgu HET Early adult 0.00
embryonic lethality prior to tooth bud stage Pik3c2atm1b(EUCOMM)Hmgu HOM E12.5 0.00
embryonic growth retardation Pik3c2atm1b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal embryo size Pik3c2atm1b(EUCOMM)Hmgu HOM E9.5 0.00
preweaning lethality, complete penetrance Pik3c2atm1b(EUCOMM)Hmgu HOM Early adult 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 9  (6/504)  (2/9) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 9  (1/504)  (2/9) N/A
Embryo 9  (1/505)  (2/9) N/A
Eye 9  (1/504)  (2/9) N/A
Foot 9  (1/504) N/A
Forebrain 9  (1/504)  (2/9) N/A
Forelimb 9  (1/504)  (2/9) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 9  (1/503) N/A
Head 9  (5/504) N/A
Heart 9  (1/504)  (2/9) N/A
Hindbrain 9  (6/504)  (2/9) N/A
Hindlimb 9  (1/503)  (2/9) N/A
Liver 9  (1/504)  (2/9) N/A
Lung 9  (1/500)  (2/9) N/A
Mandibular process 9  (1/504)  (2/9) N/A
Maxillary process 9  (1/504)  (2/9) N/A
Midbrain 9  (1/504)  (2/9) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 9  (1/504)  (2/9) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 9  (1/504) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 9  (1/504) N/A
Tail somite 9  (1/504)  (2/9) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
72 Images
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
Eye Morphology: Images Slit Lamp
5 Images
Gross Pathology and Tissue Collection
8 Images
Gross Morphology Embryo E9.5
5 Images
Combined SHIRPA and Dysmorphology
4 Images
X-ray: XRay Images Hind Leg and Hip
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Pik3c2atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pik3c2atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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