Gene: Pik3c2a

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Name
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
MGI ID
MGI:1203729
Synonyms
PI3KC2
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased hematocrit Pik3c2atm1b(EUCOMM)Hmgu HET   Early adult 4.06×10-05
enlarged lymph nodes Pik3c2atm1b(EUCOMM)Hmgu HET Early adult 0.00
embryonic growth retardation Pik3c2atm1b(EUCOMM)Hmgu HOM E9.5 0.00
hypoactivity Pik3c2atm1b(EUCOMM)Hmgu HET Early adult 4.77×10-05
preweaning lethality, complete penetrance Pik3c2atm1b(EUCOMM)Hmgu HOM   Early adult 0.00
embryonic lethality prior to tooth bud stage Pik3c2atm1b(EUCOMM)Hmgu HOM   E12.5 0.00
decreased lymphocyte cell number Pik3c2atm1b(EUCOMM)Hmgu HET Early adult 1.64×10-05
increased neutrophil cell number Pik3c2atm1b(EUCOMM)Hmgu HET Early adult 3.28×10-06
decreased mean corpuscular hemoglobin Pik3c2atm1b(EUCOMM)Hmgu HET Early adult 8.62×10-05
abnormal embryo size Pik3c2atm1b(EUCOMM)Hmgu HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64) N/A
9  (6/505)  (2/9) N/A
2  (1/73)  (2/2) N/A
9  (1/505)  (2/9) N/A
9  (1/506)  (2/9) N/A
9  (1/505)  (2/9) N/A
9  (1/505) N/A
9  (1/505)  (2/9) N/A
9  (1/505)  (2/9) N/A
2  (1/59)  (2/2) N/A
9  (1/505) N/A
9  (5/505) N/A
9  (1/505)  (2/9) N/A
9  (6/505)  (2/9) N/A
9  (1/505)  (2/9) N/A
9  (1/503)  (2/9) N/A
9  (1/503)  (2/9) N/A
9  (1/505)  (2/9) N/A
9  (1/505)  (2/9) N/A
9  (1/505)  (2/9) N/A
2  (1/75)  (2/2) N/A
9  (1/503)  (2/9) N/A
2  (1/75)  (2/2) N/A
9  (1/505) N/A
2  (1/72)  (2/2) N/A
9  (1/505) N/A
9  (1/505)  (2/9) N/A
2  (1/59)  (2/2) N/A
2  (1/59)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
67 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Gross Morphology Embryo E9.5
5 Images
Combined SHIRPA and Dysmorphology
4 Images
X-ray: XRay Images Hind Leg and Hip
3 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pik3c2atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pik3c2atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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