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Gene: Tcf7l2

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Name
transcription factor 7 like 2, T cell specific, HMG box
MGI ID
MGI:1202879
Synonyms
TCF4E TCF4B mTcf-4E mTcf-4B Tcf-4 Tcf4
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (263) All data table (813)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased total body fat amount Tcf7l2tm1a(EUCOMM)Wtsi HET Early adult 2.03×10-13
preweaning lethality, complete penetrance Tcf7l2tm1a(EUCOMM)Wtsi HOM   Early adult 0.00
increased lean body mass Tcf7l2tm1a(EUCOMM)Wtsi HET Early adult 4.05×10-09
increased bone mineral content Tcf7l2tm1a(EUCOMM)Wtsi HET Early adult 1.30×10-09
increased bone mineral density Tcf7l2tm1a(EUCOMM)Wtsi HET Early adult 3.91×10-05
decreased circulating alkaline phosphatase level Tcf7l2tm1a(EUCOMM)Wtsi HET   Early adult 1.47×10-08

Download data as:  TSV  XLS

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
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X-ray: XRay Images Whole Body Dorso Ventral
13 Images
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X-ray: XRay Images Skull Lateral Orientation
14 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
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X-ray: XRay Images Forepaw
14 Images
Legacy Phenotype Associated Images
Tcf7l2tm2a(EUCOMM)Wtsi
head, WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
forearm, WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
body, WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
head, WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
head, WT, Female, WTSI

View all 265 images

Tcf7l2tm2a(EUCOMM)Wtsi
WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
WT, Female, WTSI

View all 9 images

Tcf7l2tm1a(EUCOMM)Wtsi
embryonic lethality, fetal edema, HOM, Male, WTSI
Tcf7l2tm1a(EUCOMM)Wtsi
HOM, Female, WTSI
Tcf7l2tm1a(EUCOMM)Wtsi
embryonic lethality, fetal edema, HOM, Male, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
eye, WT, Female, WTSI
Tcf7l2tm1a(EUCOMM)Wtsi
Fused cornea and lens, HET, Female, WTSI
Tcf7l2tm1a(EUCOMM)Wtsi
narrow eye opening, HET, Male, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
back skin, WT, Female, WTSI
Tcf7l2tm2a(EUCOMM)Wtsi
back skin, WT, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tcf7l2tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tcf7l2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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