Genes Phenotypes

Gene: Tcf7l1

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Name
transcription factor 7 like 1 (T cell specific, HMG box)
MGI ID
MGI:1202876
Synonyms
Tcf3
Viability
N/A
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (0) Measurements chart (0) All data table (257)
Expression & images (45) Disease models (0) Order (1)
Significant
Not Significant
Not tested

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (2/2) N/A
Aorta 2 No  (1/589) N/A
Blood vessel 2 No  (2/2) N/A
Bone 2 No N/A
Brain 2 No  (3/589)  (2/2) N/A
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (3/589) N/A
Cerebral cortex 2 No  (2/589) N/A
Eye 2 No  (1/2) N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (1/589)  (2/2) N/A
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589)  (2/2) N/A
Large intestine 2 No  (10/589)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589)  (2/2) N/A
Lung 2 No  (1/589)  (2/2) N/A
Lymph node 2 No  (1/2) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/589) N/A
Ovary 2 No  (1/589)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/589) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/589)  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  (2/2) N/A
Prostate gland 2 No  (12/589) N/A
Skeletal muscle tissue 2 No  (1/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/589)  (2/2) N/A
Spinal cord 2 No  (2/589)  (2/2) N/A
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589)  (2/2) N/A
Striatum 2 No  (3/589) N/A
Testis 2 No  (5/589)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/589)  (2/2) N/A
Trachea 2 No  (2/589)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Tcf7l1tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
thyroid gland, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
skeletal muscle tissue, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
adrenal gland, HET, Female, WTSI

View all 22 images

Tcf7l1tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
adrenal gland, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
heart, HET, Male, WTSI

View all 12 images

Tcf7l1tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
oesophagus, stomach, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
gall bladder, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
peripheral nervous system, pituitary gland, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
spinal cord, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
skin, blood vessel, cartilage tissue, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
heart, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
blood vessel, cartilage tissue, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
skin, blood vessel, cartilage tissue, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
inguinal fat pad, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
blood vessel, cartilage tissue, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
thyroid gland, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
adrenal gland, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
mesenteric lymph node, lymph node, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
uterus, oviduct, ovary, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
inguinal fat pad, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
skin, blood vessel, cartilage tissue, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
skeletal muscle tissue, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
lung, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
eye, HET, Male, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Tcf7l1tm1a(EUCOMM)Wtsi
body, HET, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
head, WT, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
head, WT, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
body, WT, Male, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
forearm, WT, Male, WTSI

View all 197 images

Tcf7l1tm1a(EUCOMM)Wtsi
eye, corneal opacity, abnormal pupil morphology, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
eye, corneal opacity, synechia, cornea/lens fusion, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
eye, cornea/lens fusion, corneal opacity, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
eye, corneal opacity, mydriasis, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
synechia, corneal opacity, corneal ulcer, eye, HET, Female, WTSI

View all 10 images

Tcf7l1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Tcf7l1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tcf7l1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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