Psen1 | presenilin 1
Physiological systems
23 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Mortality/aging Limbs/digits/tail Homeostasis/metabolism Cardiovascular system
19 No significant impact
1 Not tested
Gene metrics:6Significant phenotypes
10Associated diseases
Expression examined in:74Adult tissues
53Embryo tissues
Human diseases caused by Psen1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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