Sorl1 | sortilin-related receptor, LDLR class A repeats-containing
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Vision/eye Nervous system Behavior/neurological Reproductive system Endocrine/exocrine gland Craniofacial Cardiovascular system Growth/size/body region
13 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
Human diseases caused by Sorl1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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