Genes Phenotypes

Gene: Sorl1

Name
sortilin-related receptor, LDLR class A repeats-containing
MGI ID
MGI:1202296
Synonyms
Sorla LR11 mSorLA 2900010L19Rik
Viability
Homozygous - Viable
Other links
MGI   Ensembl  
Significant phenotypes (3) All measurements (317) Expression & images (67) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal snout morphology Sorl1tm1b(EUCOMM)Wtsi HOM postnatal 2.64×10-05
abnormal gait Sorl1tm1b(EUCOMM)Wtsi HOM postnatal 8.88×10-07
increased fasted circulating glucose level Sorl1tm1b(EUCOMM)Wtsi HOM postnatal 2.53×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (1/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No  (1/2)  Wholemount images
Mammary gland 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No  (1/2)  Wholemount images
LacZ Wholemount Images
adipose tissue (5)
Adrenal gland expression
White Adipose Tissue expression
MA:0000116
MA:0000058
cardiovascular system (4)
Cartilage tissue expression
Bone expression
Brown adipose tissue expression
Vascular System expression
MA:0000104
MA:0001459
MA:0000057
MA:0002718
digestive system (4)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
White Adipose Tissue expression
MA:0000116
MA:0000058
exocrine system (2)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
immune system (3)
Lymph Node expression
MA:0000139
integumental system (1)
Mammary gland expression
MA:0000145
musculoskeletal system (2)
Cartilage tissue expression
Bone expression
Brown adipose tissue expression
Vascular System expression
MA:0000104
MA:0001459
MA:0000057
MA:0002718
nervous system (5)
Cerebral Cortex expression
Striatum expression
Hippocampus expression
Brain expression
MA:0000185
MA:0000891
MA:0000191
MA:0000168
postnatal mouse (26)
Adrenal gland expression
White Adipose Tissue expression
MA:0000116
MA:0000058
reproductive system (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (6)
Adrenal gland expression
White Adipose Tissue expression
MA:0000116
MA:0000058
trunk (15)
Adrenal gland expression
White Adipose Tissue expression
MA:0000116
MA:0000058
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (4/4) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (2/4) N/A
Foot 2  (1/485)  (2/4) N/A
Forebrain 2  (1/485)  (4/4) N/A
Forelimb 2  (1/485)  (2/4) N/A
Hand 2  (1/485)  (2/4) N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485)  (4/4) N/A
Hindlimb 2  (1/485)  (2/4) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485)  (2/4) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (1/4) N/A
Oral cavity 2  (1/485)  (2/4) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (4/4) N/A
Tail somite 2  (1/485)  (4/4) N/A

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Dorso Ventral
12 Images
X-ray: XRay Images Lateral Orientation
12 Images
Adult LacZ: LacZ Images Wholemount
26 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sorl1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sorl1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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