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Gene: Eomes

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Name
eomesodermin
MGI ID
MGI:1201683
Synonyms
Tbr2
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (224) All data table (430)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral content Eomestm1b(EUCOMM)Wtsi HET   Early adult 5.16×10-05
decreased lean body mass Eomestm1b(EUCOMM)Wtsi HET Early adult 9.23×10-05
embryonic lethality prior to tooth bud stage Eomestm1b(EUCOMM)Wtsi HOM   E12.5 0.00
increased total body fat amount Eomestm1b(EUCOMM)Wtsi HET Early adult 1.48×10-05
preweaning lethality, complete penetrance Eomestm1b(EUCOMM)Wtsi HOM   Early adult 0.00
embryonic lethality prior to organogenesis Eomestm1b(EUCOMM)Wtsi HOM   E9.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/590) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (1)
nervous system (2)
Brain expression
Cerebellum expression
Hypothalamus expression
Olfactory Lobe expression
MA:0000198
MA:0000168
MA:0002413
MA:0000173
postnatal mouse (3)
Brain expression
Cerebellum expression
Hypothalamus expression
Olfactory Lobe expression
MA:0000198
MA:0000168
MA:0002413
MA:0000173
reproductive system (1)
Testis expression
MA:0000411
trunk (1)
Testis expression
MA:0000411
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (1/2) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (2/2) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) Image Only N/A
Forebrain 2  (1/506)  (1/2) N/A
Forelimb 2  (1/506) N/A
Hand 2  (1/506) Image Only N/A
Head 2  (5/506)  (2/2) N/A
Heart 2  (1/506) Image Only N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

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Embryo LacZ: LacZ images wholemount
4 Images
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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
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Adult LacZ: LacZ Images Wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Eomestm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Eomestm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Eomestm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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