Genes Phenotypes

Gene: Eomes

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Name
eomesodermin
MGI ID
MGI:1201683
Synonyms
Tbr2
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (225) All data table (573)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Eomestm1b(EUCOMM)Wtsi HET postnatal 1.85×10-07
increased total body fat amount Eomestm1b(EUCOMM)Wtsi HET postnatal 4.45×10-06
preweaning lethality, complete penetrance Eomestm1b(EUCOMM)Wtsi HOM n/a 0.00
decreased bone mineral content Eomestm1b(EUCOMM)Wtsi HET postnatal 4.98×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (1)
nervous system (2)
Brain expression
Olfactory Lobe expression
Hypothalamus expression
Cerebellum expression
MA:0000168
MA:0002413
MA:0000173
MA:0000198
postnatal mouse (3)
Brain expression
Olfactory Lobe expression
Hypothalamus expression
Cerebellum expression
MA:0000168
MA:0002413
MA:0000173
MA:0000198
reproductive system (1)
Testis expression
MA:0000411
trunk (1)
Testis expression
MA:0000411
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/2) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/2) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) Image Only N/A
Forebrain 2  (1/485)  (1/2) N/A
Forelimb 2  (1/485) N/A
Hand 2  (1/485) Image Only N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485) Image Only N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Eomestm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Eomestm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Eomestm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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