Gene Summary

Name:
solute carrier family 10, member 2
Synonyms:
ASBT,  9130221J18Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
increased heart left ventricle size Slc10a2tm1b(KOMP)Mbp HOM Early adult 5.94×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
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Viewing: all phenotypes

lacZ Expression

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy Images Zygosity Mutant Expr
Kidney  Wholemount images heterozygote 100% (2 of 2)
Peyer's patch  Wholemount images heterozygote 100% (2 of 2)
Prostate gland  Wholemount images heterozygote Not available
Small intestine  Wholemount images heterozygote 100% (2 of 2)
Testis  Wholemount images heterozygote 50% (1 of 2)
Vas deferens  Wholemount images heterozygote Not available
Adrenal gland N/A heterozygote 0.0% (0 of 2)
Aorta N/A heterozygote 0.0% (0 of 2)
Bone N/A heterozygote 0.0% (0 of 2)
Brain N/A heterozygote 0.0% (0 of 2)
Brainstem N/A heterozygote 0.0% (0 of 2)
Brown adipose tissue N/A heterozygote 0.0% (0 of 2)
Cartilage tissue N/A heterozygote 0.0% (0 of 2)
Cecum N/A heterozygote 0.0% (0 of 1)
Cerebellum N/A heterozygote 0.0% (0 of 2)
Cerebral cortex N/A heterozygote 0.0% (0 of 2)
Esophagus N/A heterozygote 0.0% (0 of 2)
Eye N/A heterozygote Not available
Gall bladder N/A heterozygote 0.0% (0 of 2)
Heart N/A heterozygote 0.0% (0 of 2)
Hippocampus N/A heterozygote 0.0% (0 of 2)
Hypothalamus N/A heterozygote 0.0% (0 of 2)
Large intestine N/A heterozygote 0.0% (0 of 2)
Liver N/A heterozygote 0.0% (0 of 2)
Lower urinary tract N/A heterozygote 0.0% (0 of 2)
Lung N/A heterozygote 0.0% (0 of 2)
Lymph node N/A heterozygote 0.0% (0 of 2)
Mammary gland N/A heterozygote 0.0% (0 of 2)
Mesenteric lymph node N/A heterozygote 0.0% (0 of 2)
Olfactory lobe N/A heterozygote 0.0% (0 of 2)
Oral epithelium N/A heterozygote 0.0% (0 of 2)
Ovary N/A heterozygote 0.0% (0 of 2)
Oviduct N/A heterozygote 0.0% (0 of 2)
Pancreas N/A heterozygote 0.0% (0 of 2)
Parathyroid gland N/A heterozygote 0.0% (0 of 2)
Peripheral nervous system N/A heterozygote 0.0% (0 of 2)
Pituitary gland N/A heterozygote 0.0% (0 of 2)
Skeletal muscle N/A heterozygote 0.0% (0 of 2)
Skin N/A heterozygote 0.0% (0 of 2)
Spinal cord N/A heterozygote 0.0% (0 of 2)
Spleen N/A heterozygote 0.0% (0 of 2)
Stomach N/A heterozygote 0.0% (0 of 2)
Striatum N/A heterozygote 0.0% (0 of 2)
Thymus N/A heterozygote 0.0% (0 of 2)
Thyroid gland N/A heterozygote 0.0% (0 of 2)
Trachea N/A heterozygote 0.0% (0 of 2)
Trigeminal V nerve N/A heterozygote 0.0% (0 of 2)
Urinary bladder N/A heterozygote 0.0% (0 of 2)
Uterus N/A heterozygote 0.0% (0 of 2)
Vascular system N/A heterozygote 0.0% (0 of 2)
White adipose tissue N/A heterozygote 0.0% (0 of 2)
No Embryo expression data was found for this gene.

Background staining occurs in wild type mice and embryos at an incidental rate.

Anatomy Background staining in controls (WT)
adrenal gland 0.68% (4 of 585)
aorta 0.17% (1 of 585)
bone 0.0%
brain 0.68% (4 of 585)
brainstem 0.34% (2 of 585)
brown adipose tissue 0.0%
cartilage tissue 0.17% (1 of 585)
cecum 3.23% (12 of 371)
cerebellum 0.51% (3 of 585)
cerebral cortex 0.34% (2 of 585)
esophagus 1.71% (7 of 409)
eye 0.0%
gall bladder 0.0%
heart 0.34% (2 of 585)
hippocampus 0.51% (3 of 585)
hypothalamus 0.34% (2 of 585)
kidney 3.59% (21 of 585)
large intestine 1.71% (10 of 585)
liver 0.0%
lower urinary tract 0.17% (1 of 585)
lung 0.34% (2 of 585)
lymph node 0.17% (1 of 585)
mammary gland 0.0%
mesenteric lymph node 0.0%
olfactory lobe 0.34% (2 of 585)
oral epithelium 0.0%
ovary 0.17% (1 of 585)
oviduct 0.0%
pancreas 0.85% (5 of 585)
parathyroid gland 0.18% (1 of 563)
peripheral nervous system 0.34% (2 of 585)
peyers patch 0.0%
pituitary gland 0.17% (1 of 585)
prostate gland 2.05% (12 of 585)
skeletal muscle 0.0%
skin 0.17% (1 of 585)
small intestine 1.54% (9 of 585)
spinal cord 0.51% (3 of 585)
spleen 0.51% (3 of 585)
stomach 2.22% (13 of 585)
striatum 0.51% (3 of 585)
testis 1.03% (6 of 585)
thymus 0.17% (1 of 585)
thyroid gland 2.91% (17 of 585)
trachea 0.51% (3 of 585)
trigeminal v nerve 0.0%
urinary bladder 0.0%
uterus 0.0%
vas deferens 3.93% (15 of 382)
vascular system 0.0%
white adipose tissue 0.0%
No Embryo expression data was found for this gene.

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Skull Lateral Orientation

9 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

9 Images

X-ray

XRay Images Forepaw

9 Images

X-ray

XRay Images Whole Body Dorso Ventral

9 Images

X-ray

XRay Images Whole Body Lateral Orientation

9 Images

Adult LacZ

LacZ Images Wholemount

8 Images

Human diseases caused by Slc10a2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Slc10a2 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Bile Acid Malabsorption, Primary, 1
Failure to thrive, Chronic diarrhea, Steatorrhea, Increased fecal bile acid, Fat malabsorption OMIM:613291

The table below shows human diseases predicted to be associated to Slc10a2 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Bile Acid Malabsorption, Primary, 1
Failure to thrive, Chronic diarrhea, Steatorrhea, Increased fecal bile acid, Fat malabsorption OMIM:613291
Glycogen Storage Disease Vi
Hepatomegaly, Failure to thrive in infancy, Hyperlipidemia, Increased hepatic glycogen content, H... OMIM:232700
Bile Acid Synthesis Defect, Congenital, 3
Hepatomegaly, Acholic stools, Failure to thrive, Hepatitis, Splenomegaly, Cirrhosis, Steatorrhea,... OMIM:613812
Bile Acid Synthesis Defect, Congenital, 1
Hepatomegaly, Giant cell hepatitis, Acholic stools, Hypocholesterolemia, Failure to thrive, Hyper... OMIM:607765
Chylomicron Retention Disease
Vomiting, Hypocholesterolemia, Failure to thrive, Hypotriglyceridemia, Steatorrhea, Hypoalbuminem... OMIM:246700
Bile Acid Synthesis Defect, Congenital, 2
Hepatomegaly, Failure to thrive, Hyperbilirubinemia, Splenomegaly, Steatorrhea, Elevated circulat... OMIM:235555
Congenital Short Bowel Syndrome
Vomiting, Failure to thrive, Congenital shortened small intestine, Abnormal peristalsis, Intestin... OMIM:615237
Glycogen Storage Disease Ixa1
Hypercholesterolemia, Hepatomegaly, Hypertriglyceridemia, Elevated hepatic transaminase OMIM:306000
Lysosomal Acid Lipase Deficiency
Esophageal varix, Splenomegaly, Hepatosplenomegaly, Hypersplenism, Steatorrhea, Reduced lysosomal... OMIM:278000
Pancreatic Lipase Deficiency
Hypolipidemia, Steatorrhea, Fat malabsorption OMIM:614338
Cholesterol-Ester Transfer Protein Deficiency
Hyperlipidemia, Hyperlipoproteinemia, Hypercholesterolemia, Hypotriglyceridemia, Increased HDL ch... ORPHA:79506
Bile Acid Malabsorption, Primary, 2
Decreased circulating chenodeoxycholic acid concentration, Elevated gamma-glutamyltransferase lev... OMIM:619481
Diarrhea 7, Protein-Losing Enteropathy Type
Villous atrophy, Hyperlipidemia, Vomiting, Failure to thrive, Hypercholesterolemia, Hypoalbuminem... OMIM:615863
Neutropenia, Severe Congenital, 8, Autosomal Dominant
Elevated hepatic transaminase, Exocrine pancreatic insufficiency, Steatorrhea OMIM:618752
Hypercholanemia, Familial 1
Failure to thrive, Increased serum bile acid concentration, Steatorrhea, Fat malabsorption OMIM:607748
Congenital Bile Acid Synthesis Defect Type 2
Abnormality of the intrahepatic bile duct, Hepatomegaly, Giant cell hepatitis, Abnormal serum bil... ORPHA:79303
Congenital Disorder Of Glycosylation, Type Iip
Increased LDL cholesterol concentration, Decreased circulating ceruloplasmin concentration, Hyper... OMIM:616829
Chylomicron Retention Disease
Vomiting, Hypocholesterolemia, Failure to thrive, Increased hepatocellular lipid droplets, Hepati... ORPHA:71
Pancreatic Agenesis 2
Pancreatic hypoplasia, Steatorrhea, Small for gestational age OMIM:615935
Pancreatic Colipase Deficiency
Cholelithiasis, Chronic diarrhea, Steatorrhea, Exocrine pancreatic insufficiency, Fat malabsorption ORPHA:309108
Hypertriglyceridemia 2
Hypercholesterolemia, Decreased HDL cholesterol concentration, Hypertriglyceridemia OMIM:619324
Secondary Short Bowel Syndrome
Aganglionic megacolon, Villous atrophy, Abnormality of the small intestine, Vomiting, Failure to ... ORPHA:95427
Xanthomatosis, Susceptibility To
Hypercholesterolemia OMIM:602247
Peroxisome Biogenesis Disorder 3B
Hypocholesterolemia, Hepatomegaly, Steatorrhea, Failure to thrive OMIM:266510
Coronary Artery Disease, Autosomal Dominant, 1
Hypercholesterolemia OMIM:608320
Congenital Tufting Enteropathy
Villous atrophy, Vomiting, Failure to thrive, Weight loss, Malabsorption, Cholestatic liver disea... ORPHA:92050
Wolman Disease
Hepatomegaly, Cachexia, Esophageal varix, Splenomegaly, Steatorrhea, Hepatic failure ORPHA:75233
Citrullinemia, Type Ii, Neonatal-Onset
Decreased HDL cholesterol concentration, Failure to thrive, Hyperbilirubinemia, Hypercholesterole... OMIM:605814
Exocrine Pancreatic Insufficiency, Dyserythropoietic Anemia, And Calvarial Hyperostosis
Hepatomegaly, Failure to thrive, Splenomegaly, Steatorrhea, Exocrine pancreatic insufficiency, Ja... OMIM:612714
Sitosterolemia 2
Hypercholesterolemia, Elevated circulating sitosterol concentration OMIM:618666
Eosinophilic Gastroenteritis
Dysphagia, Elevated circulating C-reactive protein concentration, Vomiting, Weight loss, Malabsor... ORPHA:2070
Cholesteryl Ester Storage Disease
Hepatomegaly, Esophageal varix, Splenomegaly, Hypercholesterolemia, Cirrhosis, Hypertriglyceridem... ORPHA:75234
Bile Acid Synthesis Defect, Congenital, 6
Hypolipidemia, Steatorrhea OMIM:617308
Congenital Disorder Of Glycosylation, Type Iio
Hepatomegaly, Elevated hepatic transaminase, Increased LDL cholesterol concentration, Elevated ci... OMIM:616828
Morbid Obesity And Spermatogenic Failure
Decreased HDL cholesterol concentration, Increased LDL cholesterol concentration, Hypercholestero... OMIM:615703
Cholestasis, Progressive Familial Intrahepatic, 8
Hepatomegaly, Hepatic fibrosis, Esophageal varix, Bile duct proliferation, Elevated gamma-glutamy... OMIM:619662
Low Phospholipid-Associated Cholelithiasis
Cholangitis, Hepatocellular carcinoma, Sclerosing cholangitis, Biliary tract obstruction, Choleli... ORPHA:69663
Hyperlipoproteinemia, Type Ii, And Deafness
Hypercholesterolemia, Hypertriglyceridemia, Increased LDL cholesterol concentration OMIM:144300
Coronary Artery Disease, Autosomal Dominant 2
Hypercholesterolemia, Hypertriglyceridemia, Hyperlipidemia OMIM:610947
Hypothyroidism, Congenital, Nongoitrous, 8
Hypercholesterolemia, Constipation OMIM:301033
Deafness-Small Bowel Diverticulosis-Neuropathy Syndrome
Duodenal ulcer, Cachexia, Malabsorption, Chronic diarrhea, Steatorrhea ORPHA:3217
Hypercholesterolemia, Familial, 4
Hypercholesterolemia, Increased VLDL cholesterol concentration, Hypertriglyceridemia OMIM:603813
Cholestasis-Lymphedema Syndrome
Hepatomegaly, Hyperlipidemia, Malabsorption, Splenomegaly, Cirrhosis, Neonatal cholestatic liver ... OMIM:214900
Hypertriglyceridemia, Transient Infantile
Hepatomegaly, Hepatic fibrosis, Splenomegaly, Hepatic steatosis, Hypertriglyceridemia, Elevated h... OMIM:614480
Reynolds Syndrome
Hepatomegaly, Calcinosis, Hyperbilirubinemia, Splenomegaly, Gastrointestinal hemorrhage, Steatorr... OMIM:613471
Lysosomal Acid Lipase Deficiency
Microvesicular hepatic steatosis, Esophageal varix, Fatal liver failure in infancy, Hepatosplenom... ORPHA:275761
Hyperlipidemia, Familial Combined, 3
Hyperlipidemia, Increased LDL cholesterol concentration, Increased VLDL cholesterol concentration... OMIM:144250
Somatostatinoma
Hepatomegaly, Hypercalcemia, Gallbladder dysfunction, Increased circulating cortisol level, Weigh... ORPHA:97283
Glycine N-Methyltransferase Deficiency
Elevated hepatic transaminase, Hepatomegaly, Hypermethioninemia OMIM:606664
Isolated Sedoheptulokinase Deficiency
Hepatitis, Cholestatic liver disease, Steatorrhea, Cholestasis, Portal hypertension ORPHA:440713
Lipodystrophy, Congenital Generalized, Type 3
Hepatomegaly, Splenomegaly, Hypercholesterolemia, Hepatic steatosis, Hepatosplenomegaly, Hypertri... OMIM:612526
Hypercholesterolemia Due To Cholesterol 7Alpha-Hydroxylase Deficiency
Increased LDL cholesterol concentration, Acute hepatic steatosis, Hepatitis, Hypercholesterolemia... ORPHA:209902
Hyperlipoproteinemia, Type I
Hyperlipidemia, Vomiting, Nausea, Pancreatitis, Lactescent serum, Splenomegaly, Hypercholesterole... OMIM:238600
Celiac Disease, Susceptibility To, 1
Vomiting, Stomatitis, Failure to thrive, Celiac disease, Weight loss, Steatorrhea, Hypocalcemia, ... OMIM:212750
Shwachman-Diamond Syndrome 2
Hepatomegaly, High palate, Failure to thrive, Hyperechogenic pancreas, Steatorrhea, Exocrine panc... OMIM:617941
Cog4-Cdg
Recurrent infection of the gastrointestinal tract, Failure to thrive in infancy, Fatal liver fail... ORPHA:263501
Pancreatitis, Hereditary
Pancreatic calcification, Pancreatic pseudocyst, Pancreatitis, Steatorrhea, Exocrine pancreatic i... OMIM:167800
Bile Acid Synthesis Defect, Congenital, 4
Hepatomegaly, Giant cell hepatitis, Elevated hepatic transaminase, Failure to thrive, Hyperbiliru... OMIM:214950
Temple Syndrome
Cleft palate, High palate, Small for gestational age, Bifid uvula, Truncal obesity, Hypercholeste... OMIM:616222
Shwachman-Diamond Syndrome 1
Hepatomegaly, Small for gestational age, Failure to thrive, Steatorrhea, Elevated hepatic transam... OMIM:260400
Glycogen Storage Disease Due To Phosphorylase Kinase Deficiency
Hepatomegaly, Portal fibrosis, Vomiting, Hepatic fibrosis, Hepatocellular carcinoma, Failure to t... ORPHA:370
Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 1
Hypercholesterolemia, Hypoalbuminemia OMIM:607250
Abetalipoproteinemia
Hepatomegaly, Decreased HDL cholesterol concentration, Hepatic fibrosis, Vomiting, Hypocholestero... ORPHA:14
Cholestasis, Progressive Familial Intrahepatic, 2
Hepatomegaly, Hepatocellular carcinoma, Failure to thrive, Splenomegaly, Cirrhosis, Conjugated hy... OMIM:601847
Subaortic Stenosis, Membranous
Subvalvular aortic stenosis OMIM:271950
Congenital Bile Acid Synthesis Defect Type 1
Hepatomegaly, Failure to thrive, Malabsorption, Splenomegaly, Cirrhosis, Gastrointestinal hemorrh... ORPHA:79301
Autoimmune Polyendocrine Syndrome, Type Ii
Asplenia, Chronic hepatitis, Hepatitis, Cirrhosis, Steatorrhea, Exocrine pancreatic insufficiency OMIM:269200
Trichohepatoneurodevelopmental Syndrome
Hepatomegaly, High palate, Macroglossia, Cholelithiasis, Splenomegaly, Chronic diarrhea, Decrease... OMIM:618268
Growth Hormone Insensitivity Syndrome
Hypercholesterolemia, Truncal obesity, Failure to thrive ORPHA:181393
Galactokinase Deficiency
Hepatomegaly, Hypergalactosemia, Small for gestational age, Failure to thrive, Hypercholesterolem... ORPHA:79237
Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency
Hepatomegaly, Portal fibrosis, Vomiting, Nausea, Hepatic fibrosis, Failure to thrive, Elevated ci... ORPHA:264580
Glucagonoma
Hepatomegaly, Hypercalcemia, Abnormal gastrointestinal motility, Stomatitis, Increased circulatin... ORPHA:97280
Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency
Hypergalactosemia, Hyperammonemia, Gastrointestinal hemorrhage, Hepatosplenomegaly, Hyperthreonin... ORPHA:247598
Budd-Chiari Syndrome
Hepatomegaly, Gastrointestinal infarctions, Esophageal varix, Peritonitis, Weight loss, Malabsorp... ORPHA:131
Citrullinemia Type Ii
Hepatomegaly, Hypoproteinemia, Decreased HDL cholesterol concentration, Hepatic fibrosis, Vomitin... ORPHA:247585
Cystic Fibrosis
Hepatomegaly, Rectal prolapse, Failure to thrive, Pancreatitis, Cirrhosis, Hepatosplenomegaly, St... OMIM:219700
Infantile Systemic Hyalinosis
Failure to thrive, Malabsorption, Chronic diarrhea, Steatorrhea, Abnormality of the gastrointesti... ORPHA:2176
Lysinuric Protein Intolerance
Hyperglycinemia, Hyperammonemia, Increased circulating ferritin concentration, Hepatosplenomegaly... ORPHA:470
Distal Myopathy, Tateyama Type
Hypercholesterolemia, Abnormal circulating creatine kinase concentration ORPHA:488650
Neurologic, Endocrine, And Pancreatic Disease, Multisystem, Infantile-Onset 1
Hepatomegaly, Hepatic fibrosis, Failure to thrive, Hepatic steatosis, Steatorrhea, Pancreatic fib... OMIM:616263
Isolated Biliary Atresia
Hepatomegaly, Acholic stools, Elevated hepatic transaminase, Atretic gallbladder, Bile duct proli... ORPHA:30391
Hepatic Lipase Deficiency
Hypercholesterolemia, Hypertriglyceridemia, Increased HDL cholesterol concentration OMIM:614025
Analbuminemia
Hypercholesterolemia, Elevated circulating transferrin concentration, Increased LDL cholesterol c... OMIM:616000
Apolipoprotein C-Ii Deficiency
Hepatomegaly, Pancreatitis, Splenomegaly, Hypercholesterolemia, Hypertriglyceridemia, Decreased c... OMIM:207750
Parenteral Nutrition-Associated Cholestasis
Hepatomegaly, Villous atrophy, Hepatic fibrosis, Hyperlipidemia, Small for gestational age, Abnor... ORPHA:567983
Congenital Bile Acid Synthesis Defect Type 3
Bile duct proliferation, Hyperbilirubinemia, Cirrhosis, Elevated circulating aspartate aminotrans... ORPHA:79302
Systemic Primary Carnitine Deficiency
Elevated hepatic transaminase, Hepatomegaly, Vomiting ORPHA:158
Spinocerebellar Ataxia With Axonal Neuropathy Type 1
Hypercholesterolemia, Hypoalbuminemia ORPHA:94124
Disorder Of Bile Acid Synthesis
Abnormality of the liver, Cholestasis, Elevated hepatic transaminase, Biliary tract abnormality, ... ORPHA:79168
Cholestasis, Progressive Familial Intrahepatic, 1
Hepatomegaly, Failure to thrive, Cholelithiasis, Splenomegaly, Cirrhosis, Intrahepatic cholestasi... OMIM:211600
Glycogen Storage Disease Due To Liver Glycogen Phosphorylase Deficiency
Hepatomegaly, Hepatic fibrosis, Portal fibrosis, Hyperlipidemia, Increased hepatic glycogen conte... ORPHA:369
Pancreatic Triacylglycerol Lipase Deficiency
Colitis, Weight loss, Steatorrhea, Exocrine pancreatic insufficiency, Diarrhea ORPHA:309031
Glycogen Storage Disease Due To Liver And Muscle Phosphorylase Kinase Deficiency
Hepatomegaly, Hepatic fibrosis, Vomiting, Nausea, Hepatocellular carcinoma, Elevated circulating ... ORPHA:79240
Combined Oxidative Phosphorylation Deficiency 30
Failure to thrive, Hyperalaninemia, Decreased liver function, Elevated hepatic transaminase, Gast... OMIM:616974
Inflammatory Pseudotumor Of The Liver
Vomiting, Nausea, Weight loss, Abnormal liver sonography, Neoplasm of the liver, Cirrhosis, Eleva... ORPHA:90003
Ataxia With Vitamin E Deficiency
Hypercholesterolemia, Xanthelasma, Hypertriglyceridemia, Increased LDL cholesterol concentration OMIM:277460
Neutral Lipid Storage Disease With Myopathy
Hepatomegaly, Elevated circulating creatine kinase concentration, Hepatic steatosis, Hypertriglyc... OMIM:610717
Pearson Syndrome
Hepatomegaly, Dysphagia, Small for gestational age, Macronodular cirrhosis, Hypokalemia, Median c... ORPHA:699
Cholestasis, Progressive Familial Intrahepatic, 6
Elevated hepatic transaminase, Failure to thrive, Elevated gamma-glutamyltransferase level, Chron... OMIM:619484
Temple Syndrome Due To Paternal 14Q32.2 Hypomethylation
Hypercholesterolemia, Obesity, High palate ORPHA:254531
Lipodystrophy, Familial Partial, Type 7
Hypercholesterolemia, Pancreatitis, Hypertriglyceridemia OMIM:606721
Hypercholesterolemia, Familial, 3
Hypercholesterolemia, Xanthelasma, Abnormal LDL cholesterol concentration OMIM:603776
Mitochondrial Complex Iii Deficiency, Nuclear Type 5
Small for gestational age, Hyperammonemia, Decreased liver function, Hyperalaninemia, Elevated ci... OMIM:615160
Benign Recurrent Intrahepatic Cholestasis
Acholic stools, Hepatocellular carcinoma, Weight loss, Pancreatitis, Cholelithiasis, Cholestatic ... ORPHA:65682
Liver Failure, Infantile, Transient
Microvesicular hepatic steatosis, Hepatomegaly, Vomiting, Hyperbilirubinemia, Macrovesicular hepa... OMIM:613070
Cholestasis, Progressive Familial Intrahepatic, 3
Hepatomegaly, Portal fibrosis, Bile duct proliferation, Malabsorption, Splenomegaly, Cirrhosis, E... OMIM:602347
Temple Syndrome Due To Maternal Uniparental Disomy Of Chromosome 14
Pyloric stenosis, Cleft palate, High palate, Small for gestational age, Bifid uvula, Truncal obes... ORPHA:96184
Immunodeficiency 47
Hepatomegaly, Hepatic fibrosis, Elevated hepatic transaminase, Failure to thrive, Splenomegaly, C... OMIM:300972
Shwachman-Diamond Syndrome
Hepatomegaly, Pancreatic hypoplasia, Failure to thrive, Hypoamylasemia, Increased serum bile acid... ORPHA:811
Hypercholesterolemia, Familial, 2
Hypercholesterolemia, Xanthelasma, Increased LDL cholesterol concentration OMIM:144010
Citrullinemia, Type Ii, Adult-Onset
Hepatic fibrosis, Ballooning hepatocyte degeneration, Hepatocellular carcinoma, Pancreatitis, Ele... OMIM:603471
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)
Microvesicular hepatic steatosis, Failure to thrive, Cirrhosis, Cholestasis, Hepatic failure, Hyp... OMIM:617156
Congenital Generalized Lipodystrophy
Hepatomegaly, Failure to thrive, Macroglossia, Hypercholesterolemia, Hepatic steatosis, Cirrhosis... ORPHA:528
Dysbetalipoproteinemia
Hepatomegaly, Decreased HDL cholesterol concentration, Increased LDL cholesterol concentration, H... ORPHA:412
Hepatitis, Fulminant Viral, Susceptibility To
Hepatomegaly, Nausea, Fulminant hepatitis, Hepatic failure, Elevated hepatic transaminase, Jaundice OMIM:618549
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency
Elevated hepatic transaminase, Abnormality of the gastrointestinal tract, Hyperlipidemia, Failure... ORPHA:2089
Gallbladder Disease 1
Cholangitis, Hepatic fibrosis, Cholelithiasis, Pancreatitis, Cholesterol gallstones, Elevated cir... OMIM:600803
Abdominal Obesity-Metabolic Syndrome 3
Hypercholesterolemia, Abdominal obesity, Truncal obesity OMIM:615812
Glycogen Storage Disease Iii
Hepatomegaly, Hepatic fibrosis, Hyperlipidemia, Elevated circulating creatine kinase concentratio... OMIM:232400
Sapho Syndrome
Chronic diarrhea, Inflammation of the large intestine, Steatorrhea, Malabsorption ORPHA:793
Congenital Analbuminemia
Hypoproteinemia, Small for gestational age, Hyperlipidemia, Hypercholesterolemia, Hypoalbuminemia... ORPHA:86816
Laron Syndrome
Hypercholesterolemia, Truncal obesity ORPHA:633
Smith-Magenis Syndrome
Constipation, Velopharyngeal insufficiency, Hypercholesterolemia, Hypertriglyceridemia, Increased... OMIM:182290
Myelodysplasia, Immunodeficiency, Facial Dysmorphism, Short Stature, And Psychomotor Delay
Decreased body weight, Steatorrhea OMIM:601347
Gallbladder Neuroendocrine Tumor
Nausea, Elevated alkaline phosphatase of hepatic origin, Biliary tract obstruction, Biliary tract... ORPHA:100086
Sitosterolemia 1
Elevated circulating sitosterol concentration, Splenomegaly, Hypercholesterolemia, Abnormality of... OMIM:210250
Idiopathic Steroid-Resistant Nephrotic Syndrome
Peritonitis, Abnormal circulating lipid concentration, Hypercholesterolemia, Hypertriglyceridemia... ORPHA:567548
Glycogen Storage Disease Ixc
Hepatomegaly, Increased hepatic glycogen content, Bile duct proliferation, Splenomegaly, Cirrhosi... OMIM:613027
Carnitine Palmitoyltransferase I Deficiency
Hepatomegaly, Elevated circulating creatine kinase concentration, Hyperammonemia, Hepatic steatos... OMIM:255120
Morgagni-Stewart-Morel Syndrome
Hypercholesterolemia, Obesity, Hyperuricemia ORPHA:77296
Biliary Atresia, Extrahepatic
Hepatomegaly, Unconjugated hyperbilirubinemia, Portal fibrosis, Acholic stools, Atretic gallbladd... OMIM:210500
Peutz-Jeghers Syndrome
Rectal prolapse, Abnormality of the gallbladder, Stomach cancer, Vomiting, Gastrointestinal infar... ORPHA:2869
Bile Acid Synthesis Defect, Congenital, 5
Hepatomegaly, Portal fibrosis, Hepatic fibrosis, Increased total iron binding capacity, Hyperbili... OMIM:616278
Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia
Hypercholesterolemia, Hypoalbuminemia OMIM:208920
Congenital Disorder Of Glycosylation, Type Iij
Recurrent infection of the gastrointestinal tract, Hepatomegaly, Failure to thrive, Splenomegaly,... OMIM:613489
Hypermethioninemia Due To Adenosine Kinase Deficiency
Portal fibrosis, Failure to thrive, Hyperbilirubinemia, Decreased liver function, Hepatic steatos... OMIM:614300
Nephrotic Syndrome, Type 11
Hypercholesterolemia, High palate, Cleft palate, Hypoalbuminemia OMIM:616730
Caroli Disease
Cholangitis, Cholangiocarcinoma, Esophageal varix, Splenomegaly, Conjugated hyperbilirubinemia, E... ORPHA:53035
Pyruvate Dehydrogenase E3 Deficiency
Hepatomegaly, Hyperisoleucinemia, Vomiting, Failure to thrive, Hyperammonemia, Elevated plasma br... ORPHA:2394
9Q31.1Q31.3 Microdeletion Syndrome
Hypercholesterolemia, Overweight ORPHA:401923
Mitochondrial Dna Depletion Syndrome 6 (Hepatocerebral Type)
Microvesicular hepatic steatosis, Hepatomegaly, Vomiting, Elevated hepatic transaminase, Failure ... OMIM:256810
Spinocerebellar Ataxia With Axonal Neuropathy Type 2
Dysphagia, Elevated circulating creatine kinase concentration, Hypercholesterolemia, Elevated alp... ORPHA:64753
Carnitine Palmitoyltransferase Ii Deficiency, Infantile
Hepatomegaly, Vomiting, Elevated circulating creatine kinase concentration, Hyperammonemia, Macro... OMIM:600649
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)
Hepatomegaly, Hepatocellular necrosis, Vomiting, Failure to thrive, Depletion of mitochondrial DN... OMIM:251880
Mitochondrial Dna Depletion Syndrome 16 (Hepatic Type)
Hepatomegaly, Increased total bilirubin, Cholestasis, Hepatic failure, Elevated hepatic transamin... OMIM:618528
Carnitine Palmitoyl Transferase 1A Deficiency
Elevated hepatic transaminase, Transient hyperlipidemia, Hepatomegaly, Hepatic failure ORPHA:156
Mitchell-Riley Syndrome
Pancreatic hypoplasia, Duodenal atresia, Acholic stools, Annular pancreas, Hyperbilirubinemia, Ma... OMIM:615710
Carnitine Deficiency, Systemic Primary
Decreased carnitine level in liver, Hepatomegaly, Vomiting, Failure to thrive, Hyperammonemia, He... OMIM:212140
Isolated Thyroid-Stimulating Hormone Deficiency
Neonatal hyperbilirubinemia, Failure to thrive, Macroglossia, Abnormal circulating thyroglobulin ... ORPHA:90674
Refractory Celiac Disease
Jejunitis, Hypoproteinemia, Villous atrophy, Weight loss, Elevated alkaline phosphatase of bone o... ORPHA:398063
Bardet-Biedl Syndrome 20
Hypercholesterolemia, Obesity, Pancreatitis, Elevated hepatic transaminase OMIM:619471
Smith-Magenis Syndrome
Failure to thrive in infancy, Cleft palate, Hypercholesterolemia, Hypertriglyceridemia, Obesity, ... ORPHA:819
Proprotein Convertase 1/3 Deficiency
Villous atrophy, Malabsorption, Obesity, Diarrhea, Decreased circulating cortisol level OMIM:600955
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ib
Hepatomegaly, Inflammation of the large intestine, Hyperlipidemia, Increased hepatic glycogen con... ORPHA:79259
Deafness, Nerve Type, With Mesenteric Diverticula Of Small Bowel And Progressive Sensory Neuropathy
Hypoproteinemia, Small bowel diverticula, Jejunoileal ulceration, Fat malabsorption OMIM:221400
Infantile Liver Failure Syndrome 2
Vomiting, Hyperammonemia, Acute hepatic failure, Elevated hepatic transaminase, Jaundice OMIM:616483
Gaisböck Syndrome
Hyperproteinemia, Cholecystitis, Increased circulating renin level, Hyperuricemia, Hypercholester... ORPHA:90041
Cholestasis, Intrahepatic, Of Pregnancy, 1
Abnormal liver function tests during pregnancy, Elevated hepatic transaminase, Increased serum bi... OMIM:147480
Medium Chain Acyl-Coa Dehydrogenase Deficiency
Hepatomegaly, Cachexia, Vomiting, Elevated circulating creatine kinase concentration, Hyperammone... ORPHA:42
Hyperinsulinism Due To Short Chain 3-Hydroxylacyl-Coa Dehydrogenase Deficiency
Vomiting, Decreased 3-hydroxyacyl-CoA dehydrogenase level, Failure to thrive, Hepatic necrosis, A... ORPHA:71212
Acquired Aneurysmal Subarachnoid Hemorrhage
Hypercholesterolemia, Vomiting, Nausea ORPHA:90065
Protoporphyria, Erythropoietic, X-Linked
Elevated hepatic transaminase, Increased erythrocyte protoporphyrin concentration, Cholelithiasis OMIM:300752
Portal Hypertension, Noncirrhotic, 1
Hepatomegaly, Esophageal varix, Splenomegaly, Elevated hepatic transaminase, Portal hypertension OMIM:617068
Galloway-Mowat Syndrome 7
Hypercholesterolemia, High palate, Cleft palate OMIM:618348
Intrahepatic Cholestasis Of Pregnancy
Small for gestational age, Hyperbilirubinemia, Abnormality of the pancreas, Increased serum bile ... ORPHA:69665
Mandibuloacral Dysplasia
High palate, Increased circulating free fatty acid level, Hypercholesterolemia, Abnormal tongue m... ORPHA:2457
Mirizzi Syndrome
Gallbladder perforation, Vomiting, Nausea, Cholelithiasis, Pancreatitis, Hyperbilirubinemia, Chol... ORPHA:521219
Alagille Syndrome 1
Hepatocellular carcinoma, Elevated hepatic transaminase, Failure to thrive, Hypercholesterolemia,... OMIM:118450
Megalocornea-Mental Retardation Syndrome
Hypercholesterolemia, Dysphagia, High palate, Bifid uvula OMIM:249310
Hepatoportal Sclerosis
Esophageal varix, Hepatocellular carcinoma, Hyperbilirubinemia, Nodular regenerative hyperplasia ... ORPHA:64743
Maternal Uniparental Disomy Of Chromosome 4
Hypocholesterolemia, Elevated circulating creatine kinase concentration, Abetalipoproteinemia, De... ORPHA:96180
Hemolytic Anemia, Nonspherocytic, Due To Glucose Phosphate Isomerase Deficiency
Pigment gallstones, Cholelithiasis, Splenomegaly, Cholecystitis, Decreased glucosephosphate isome... OMIM:613470
Blue Diaper Syndrome
Hypercalcemia, Elevated hepatic transaminase, Diarrhea, Hyperphosphatemia, Increased body weight ORPHA:94086
Lipodystrophy, Familial Partial, Type 2
Hepatomegaly, Decreased HDL cholesterol concentration, Hypercholesterolemia, Hepatic steatosis, A... OMIM:151660
Sclerosing Cholangitis, Neonatal
Hepatomegaly, Splenomegaly, Cirrhosis, Cholestasis, Elevated hepatic transaminase, Biliary cirrho... OMIM:617394
Metachromatic Leukodystrophy
Gallbladder dysfunction, Cholecystitis OMIM:250100
Caroli Syndrome
Abnormality of the intrahepatic bile duct, Cholangitis, Cholangiocarcinoma, Esophageal varix, Mel... ORPHA:480520
Primary Biliary Cholangitis/Primary Sclerosing Cholangitis And Autoimmune Hepatitis Overlap Syndrome
Abnormality of the intrahepatic bile duct, Inflammation of the large intestine, Interface hepatit... ORPHA:562639
Corticosteroid-Sensitive Aseptic Abscess Syndrome
Elevated circulating C-reactive protein concentration, Weight loss, Abnormality of the pancreas, ... ORPHA:54251
Familial Pancreatic Carcinoma
Intestinal pseudo-obstruction, Peritoneal abscess, Functional intestinal obstruction, Weight loss... ORPHA:1333
Hyperinsulinism Due To Hnf4A Deficiency
Hepatomegaly, Vomiting, Increased hepatic glycogen content, Abnormal circulating fatty-acid conce... ORPHA:263455
Palmoplantar Hyperkeratosis With Squamous Cell Carcinoma Of Skin And 46,Xx Sex Reversal
Hypercholesterolemia, Hypertriglyceridemia OMIM:610644
Pyruvate Kinase Deficiency Of Red Cells
Unconjugated hyperbilirubinemia, Cholelithiasis, Splenomegaly, Cholecystitis, Jaundice OMIM:266200
Hemolytic Anemia, Nonspherocytic, Due To Hexokinase Deficiency
Hyperbilirubinemia, Cholelithiasis, Splenomegaly, Cholecystitis, Jaundice OMIM:235700
Megalocornea-Intellectual Disability Syndrome
Hypercholesterolemia, High palate ORPHA:2479
Amoebiasis Due To Entamoeba Histolytica
Bloody diarrhea, Protracted diarrhea, Gastrointestinal dysmotility, Acute colitis, Weight loss, I... ORPHA:67
Acyl-Coa Dehydrogenase, Medium-Chain, Deficiency Of
Hepatomegaly, Vomiting, Hepatic steatosis, Elevated hepatic transaminase, Decreased plasma carnitine OMIM:201450
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Hepatomegaly, Hypoproteinemia, Vomiting, Small for gestational age, Elevated circulating creatine... ORPHA:26793
Portal Hypertension, Noncirrhotic, 2
Hepatomegaly, Esophageal varix, Hepatocellular carcinoma, Nodular regenerative hyperplasia of liv... OMIM:619463
Lmna-Related Cardiocutaneous Progeria Syndrome
Hypercholesterolemia, Abnormality of the intrahepatic bile duct, Hypertriglyceridemia ORPHA:363618
Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 4
Failure to thrive, Elevated circulating creatine kinase concentration, Gastroparesis, Abnormality... OMIM:610131
Lipodystrophy, Congenital Generalized, Type 4
Pyloric stenosis, Hepatomegaly, Dysphagia, Failure to thrive, Elevated circulating creatine kinas... OMIM:613327
Primary Hepatic Neuroendocrine Carcinoma
Hepatomegaly, Nausea, Elevated alkaline phosphatase of hepatic origin, Biliary tract obstruction,... ORPHA:100085
Autoimmune Hepatitis
Inflammation of the large intestine, Hepatocellular carcinoma, Sclerosing cholangitis, Fulminant ... ORPHA:2137
Neutral Lipid Storage Myopathy
Hepatomegaly, Abnormal circulating creatine kinase concentration, Hepatic steatosis, Increased ci... ORPHA:98908
Autosomal Recessive Polycystic Kidney Disease
Abnormality of the intrahepatic bile duct, Cholangitis, Cholangiocarcinoma, Esophageal varix, Spl... ORPHA:731
Primary Sclerosing Cholangitis
Neoplasm of the gallbladder, Cholangiocarcinoma, Hepatitis, Splenomegaly, Hepatosplenomegaly, Ade... ORPHA:171
Erythrocytosis, Familial, 8
Jaundice, Cholelithiasis, Cholecystitis, Splenomegaly OMIM:222800
Secondary Intestinal Lymphangiectasia
Decreased prealbumin level, Vomiting, Celiac disease, Hypocholesterolemia, Reduced circulating tr... ORPHA:90363
Infantile Liver Failure Syndrome 3
Hepatomegaly, Splenomegaly, Hyperammonemia, Hepatic steatosis, Acute hepatic failure, Cholestasis... OMIM:618641
Anemia, Sideroblastic, 3, Pyridoxine-Refractory
Hepatomegaly, Elevated hepatic iron concentration, Splenomegaly, Cirrhosis, Increased circulating... OMIM:616860
Biliary, Renal, Neurologic, And Skeletal Syndrome
Esophageal varix, Splenomegaly, Increased circulating ferritin concentration, Conjugated hyperbil... OMIM:619534
Glycogen Storage Disease Ia
Hepatomegaly, Hyperlipidemia, Hepatocellular carcinoma, Pancreatitis, Hyperuricemia, Intermittent... OMIM:232200
Ileal Neuroendocrine Tumor
Gastrointestinal obstruction, Nausea, Small intestine carcinoid, Functional intestinal obstructio... ORPHA:100078
Jejunal Neuroendocrine Tumor
Gastrointestinal obstruction, Nausea, Small intestine carcinoid, Functional intestinal obstructio... ORPHA:100077
Proteasome-Associated Autoinflammatory Syndrome 3
Hepatomegaly, Failure to thrive, Splenomegaly, Hypertriglyceridemia, Elevated hepatic transaminase OMIM:617591
Glycogen Storage Disease Xii
Jaundice, Cholelithiasis, Cholecystitis, Splenomegaly OMIM:611881
Triploidy
Hepatomegaly, Cleft palate, Abnormality of the gallbladder, Macroglossia, Intestinal malrotation,... ORPHA:3376
Tyrosinemia, Type I
Hepatomegaly, Hepatocellular carcinoma, Failure to thrive, Hypertyrosinemia, Splenomegaly, Cirrho... OMIM:276700
Hardikar Syndrome
Cholangitis, Esophageal varix, Intrahepatic bile duct cysts, Splenomegaly, Hepatosplenomegaly, Hy... OMIM:301068
Abetalipoproteinemia
Abetalipoproteinemia, Fat malabsorption OMIM:200100
Hereditary Hemorrhagic Telangiectasia
Esophageal varix, Cholelithiasis, Cirrhosis, Gastrointestinal hemorrhage, Intestinal polyposis, H... ORPHA:774
Glycogen Storage Disease Ib
Hepatomegaly, Hepatocellular carcinoma, Hyperlipidemia, Pancreatitis, Hyperuricemia, Xanthelasma,... OMIM:232220
Fructose Intolerance, Hereditary
Hepatomegaly, Vomiting, Nausea, Failure to thrive, Hypophosphatemia, Hyperbilirubinemia, Hyperuri... OMIM:229600
Duodenal Neuroendocrine Tumor
Gastrointestinal obstruction, Nausea, Functional intestinal obstruction, Insulinoma, Melena, Inte... ORPHA:100076
Rett Syndrome
Failure to thrive, Increased serum pyruvate, Hyperammonemia, Cholecystitis ORPHA:778
Neuroendocrine Neoplasm Of Appendix
Hepatomegaly, Midgut malrotation, Protracted diarrhea, Primary hypercortisolism, Functional intes... ORPHA:100079
Fucosidosis
Failure to thrive, Hepatomegaly, Abnormality of the gallbladder ORPHA:349
Hepatocellular Carcinoma
Hepatomegaly, Hyponatremia, Hypercalcemia, Esophageal varix, Hemobilia, Elevated hepatic transami... ORPHA:88673
Steinert Myotonic Dystrophy
Elevated hepatic transaminase, Intestinal pseudo-obstruction, Cholelithiasis, Hypercholesterolemi... ORPHA:273
Oculocerebrorenal Syndrome Of Lowe
Hyponatremia, Hypokalemia, Failure to thrive, Hypophosphatemia, Malabsorption, Hypercholesterolem... ORPHA:534
Lowe Oculocerebrorenal Syndrome
Failure to thrive, Elevated maternal serum alpha-fetoprotein, Hypercholesterolemia, Elevated amni... OMIM:309000
Q Fever
Hepatomegaly, Weight loss, Hepatitis, Splenomegaly, Abnormality of the liver, Hepatosplenomegaly,... ORPHA:781
Vacterl/Vater Association
Cleft palate, Abnormality of the gallbladder, Anal atresia, Abnormality of the pancreas, Anorecta... ORPHA:887
Homozygous Familial Hypercholesterolemia
Hypercholesterolemia, Hepatic steatosis, Increased LDL cholesterol concentration, Hyperlipidemia ORPHA:391665
Triosephosphate Isomerase Deficiency
Jaundice, Cholelithiasis, Cholecystitis, Splenomegaly OMIM:615512
Genitopalatocardiac Syndrome
Cleft palate, Abnormality of the gallbladder, Abnormality of mesentery morphology ORPHA:2075
Intellectual Developmental Disorder, X-Linked, Syndromic, With Pigmentary Mosaicism And Coarse Facies
Hepatomegaly, Cleft palate, Cholelithiasis, Hepatosplenomegaly, Cholecystitis, Obesity, Chronic c... OMIM:301066
Recurrent Infections Associated With Rare Immunoglobulin Isotypes Deficiency
Cholangitis, Celiac disease, Chronic gastritis, Cholecystitis, Viral hepatitis, Liver abscess ORPHA:183675
Metachromatic Leukodystrophy, Adult Form
Bowel incontinence, Neoplasm of the gallbladder, Cholecystitis ORPHA:309271
Listeriosis
Splenic abscess, Vomiting, Peritonitis, Nausea, Liver abscess, Cholecystitis, Hepatic granulomato... ORPHA:533
Igg4-Related Kidney Disease
Abnormality of mesentery morphology, Retroperitoneal fibrosis, Weight loss, Elevated circulating ... ORPHA:449395
Crimean-Congo Hemorrhagic Fever
Hepatomegaly, Elevated circulating creatine kinase concentration, Melena, Splenomegaly, Parotitis... ORPHA:99827
Metachromatic Leukodystrophy, Late Infantile Form
Cholecystitis ORPHA:309256
Metachromatic Leukodystrophy, Juvenile Form
Cholecystitis ORPHA:309263
Smith-Lemli-Opitz Syndrome
Pyloric stenosis, Aganglionic megacolon, Cleft palate, Abnormality of the gallbladder, Elevated 7... ORPHA:818
Kawasaki Disease
Hepatitis, Glossitis, Cholecystitis, Diarrhea, Jaundice ORPHA:2331
Wolf-Hirschhorn Syndrome
Failure to thrive, Abdominal situs inversus, Abnormality of the gallbladder, Cleft palate ORPHA:280
Storm Syndrome
Fat malabsorption OMIM:185069

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Slc10a2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Slc10a2.

No publications found that use IMPC mice or data for Slc10a2.

Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Slc10a2tm2a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Slc10a2tm2e(KOMP)Mbp Targeted, non-conditional allele ES Cells
Slc10a2tm1b(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Mice, Tissue
Slc10a2tm1e(KOMP)Mbp Targeted, non-conditional allele ES Cells
Slc10a2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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