Limk2 | LIM domain kinase 2
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Mortality/aging
14 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased startle reflex | 5 supporting datasets | Limk2tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.52x10-14 | ||
preweaning lethality, incomplete penetrance | 1 supporting dataset | Limk2tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
increased body length | 1 supporting dataset | Limk2tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.83x10-5 | ||
increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Limk2tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.71x10-5 | ||
long tibia | 1 supporting dataset | Limk2tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 6.67x10-5 | ||
abnormal locomotor activation | 1 supporting dataset | Limk2tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 5.01x10-5 |
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External links
No external links available for Limk2.
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Limk2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |