Limk2 | LIM domain kinase 2

GeneMGI:1197517Synonyms: A930024P04Rik, LIM kinase 2, +3 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex5 supporting datasetsLimk2tm1a(EUCOMM)WtsiheterozygoteEarly adult1.52x10-14 
preweaning lethality, incomplete penetrance1 supporting datasetLimk2tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased body length1 supporting datasetLimk2tm1a(EUCOMM)WtsiheterozygoteEarly adult1.83x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetLimk2tm1a(EUCOMM)WtsiheterozygoteEarly adult3.71x10-5 
long tibia1 supporting datasetLimk2tm1a(EUCOMM)WtsiheterozygoteEarly adult6.67x10-5 
abnormal locomotor activation1 supporting datasetLimk2tm1a(EUCOMM)WtsiheterozygoteEarly adult5.01x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Limk2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter