Gene: Irx1

Log in to follow
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal heart morphology Irx1tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal hindbrain morphology Irx1tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal craniofacial morphology Irx1tm1.1(KOMP)Vlcg HOM E12.5 0.00
preweaning lethality, complete penetrance Irx1tm1.1(KOMP)Vlcg HOM   Early adult 0.00
increased thigmotaxis Irx1tm1.1(KOMP)Vlcg HET Early adult 5.45×10-05
abnormal behavior Irx1tm1.1(KOMP)Vlcg HET Early adult 5.46×10-05
decreased grip strength Irx1tm1.1(KOMP)Vlcg HET Early adult 4.47×10-05
abnormal forebrain morphology Irx1tm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal neural tube closure Irx1tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal embryo size Irx1tm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal embryo size Irx1tm1.1(KOMP)Vlcg HET E15.5 0.00
hypoactivity Irx1tm1.1(KOMP)Vlcg HET Early adult 8.21×10-05
abnormal forebrain morphology Irx1tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal embryo size Irx1tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal abdominal wall morphology Irx1tm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal midbrain morphology Irx1tm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal cranium morphology Irx1tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal embryo size Irx1tm1.1(KOMP)Vlcg HOM E15.5 0.00
abnormal cranium morphology Irx1tm1.1(KOMP)Vlcg HOM E12.5 0.00
decreased total body fat amount Irx1tm1.1(KOMP)Vlcg HET Early adult 1.36×10-07
abnormal hindbrain morphology Irx1tm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal midbrain morphology Irx1tm1.1(KOMP)Vlcg HET E12.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Brain 2 No  (3/590)  (2/2)  Section images
Brainstem 2 No  (2/590)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (3/590)  (2/2)  Section images
Cerebral cortex 2 No  (2/590) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Section images
Heart 2 No  (1/590)  Section images
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590)  (2/2)  Section images
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/590)  (2/2)  Section images
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/590)  (2/2)  Section images
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (1/2)  Section images
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/590)  (2/2)  Section images
Spinal cord 2 No  (2/590)  (2/2)  Section images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2)  Section images
Striatum 2 No  (3/590) N/A
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (5/590)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  Section images
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590)  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/3) N/A
Dorsal root ganglion 2  (1/61)  (1/3) N/A
Ear 2  (1/506)  (2/3) N/A
Embryo 2  (1/507)  (2/3)  Wholemount images
Eye 2  (1/506)  (2/3) N/A
Foot 2  (1/506)  (2/3) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506)  (2/3) N/A
Fronto-nasal process 2  (1/62) Image Only N/A
Hand 2  (1/506)  (2/3) N/A
Head 2  (5/506)  (2/3) N/A
Heart 2  (1/506)  (2/3) N/A
Hindbrain 2  (6/506)  (2/3) N/A
Hindlimb 2  (1/506)  (2/3) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) Image Only N/A
Mandibular process 2  (1/506)  (2/3) N/A
Maxillary process 2  (1/506)  (2/3) N/A
Midbrain 2  (1/506)  (2/3) N/A
Nose 2  (1/76)  (1/3) N/A
Oral cavity 2  (1/504) Image Only N/A
Skin 2  (1/506)  (1/3) N/A
Spinal cord 2  (1/73)  (2/3) N/A
Tail 2  (1/506)  (2/3) N/A
Tail somite 2  (1/506) Image Only N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
12 Images
Original Image
Adult LacZ: LacZ Images Section
28 Images
X-ray: XRay Images Forepaw
9 Images
Gross Morphology Embryo E12.5
6 Images
Eye Morphology: Images Slit Lamp
2 Images
Eye Morphology: Images Ophthalmoscopy
2 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Irx1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Irx1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter