Gene: Pole2

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Name
polymerase (DNA directed), epsilon 2 (p59 subunit)
MGI ID
MGI:1197514
Synonyms
DNA polymerase epsilon small subunit
Embryo viewer
N/A
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Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo turning Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal skin morphology Pole2em1(IMPC)Mbp HET Late adult 0.00
increased hemoglobin content Pole2em1(IMPC)Mbp HET Late adult 8.62×10-07
thrombocytosis Pole2em1(IMPC)Mbp HET Early adult 2.29×10-05
preweaning lethality, complete penetrance Pole2em1(IMPC)Mbp HOM Early adult 0.00
abnormal neural tube closure Pole2em1(IMPC)Mbp HET E9.5 0.00
increased prepulse inhibition Pole2em1(IMPC)Mbp HET Early adult 1.14×10-08
abnormal hindbrain development Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal midbrain development Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal forebrain development Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal heart morphology Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal otic vesicle morphology Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal optic vesicle formation Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal allantois morphology Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal heart looping Pole2em1(IMPC)Mbp HET E9.5 0.00
abnormal pharyngeal arch morphology Pole2em1(IMPC)Mbp HET E9.5 0.00

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
39 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
X-ray: XRay Images Whole Body Dorso Ventral
30 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pole2em1(IMPC)Mbp Exon Deletion Mice, Tissue
Pole2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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