Gene: Dsg2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased cardiac muscle contractility Dsg2tm1b(EUCOMM)Wtsi HOM Early adult 6.95×10-07
dilated heart left ventricle Dsg2tm1b(EUCOMM)Wtsi HOM   Early adult 4.40×10-07
abnormal coat appearance Dsg2tm1b(EUCOMM)Wtsi HOM Early adult 7.09×10-07

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cecum 2 No  (12/371)  (2/2) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583)  (2/2)  Wholemount images
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/382) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
9 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dsg2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Dsg2tm48337(pL1L2_GT0_DelLacZ_bsd) Targeting vectors
Dsg2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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