Genes Phenotypes

Gene: Dsg2

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Name
desmoglein 2
MGI ID
MGI:1196466
Synonyms
D18Ertd293e
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (172) All data table (478)
Expression & images (51) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal coat appearance Dsg2tm1b(EUCOMM)Wtsi HOM Early adult 7.51×10-07
decreased cardiac muscle contractility Dsg2tm1b(EUCOMM)Wtsi HOM Early adult 3.16×10-06
dilated heart left ventricle Dsg2tm1b(EUCOMM)Wtsi HOM Early adult 4.39×10-06

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379)  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (1)
Heart expression
MA:0000072
digestive system (2)
Large Intestine expression
MA:0000333
endocrine system (1)
Parathyroid gland expression
MA:0000128
exocrine system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
nervous system (2)
Striatum expression
Brain expression
MA:0000891
MA:0000168
postnatal mouse (9)
Heart expression
MA:0000072
reproductive system (2)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
trunk (6)
Heart expression
MA:0000072
urinary system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
9 Images
Eye Morphology: VIP of right eye
8 Images
Eye Morphology: VIP of right fundus
7 Images
Eye Morphology: VIP of left fundus
8 Images
Eye Morphology: VIP of left eye
8 Images

 Disease Models

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MGI Allele Allele Type Produced
Dsg2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Dsg2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dsg2tm48337(pL1L2_GT0_DelLacZ_bsd) Targeting vectors

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