Gene: Hgsnat

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Name
heparan-alpha-glucosaminide N-acetyltransferase
MGI ID
MGI:1196297
Synonyms
9430010M12Rik Tmem76 D8Ertd354e
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Hgsnatem4(IMPC)Tcp HOM Early adult 9.65×10-05
enlarged urinary bladder Hgsnatem4(IMPC)Tcp HOM Early adult 0.00
increased circulating alkaline phosphatase level Hgsnatem4(IMPC)Tcp HOM Early adult 1.19×10-05
abnormal bone structure Hgsnatem4(IMPC)Tcp HOM Early adult 1.38×10-08
abnormal lung morphology Hgsnatem4(IMPC)Tcp HOM Early adult 0.00
enlarged lymph nodes Hgsnatem4(IMPC)Tcp HOM Early adult 0.00
increased lean body mass Hgsnatem4(IMPC)Tcp HOM Early adult 3.81×10-08
short tibia Hgsnatem4(IMPC)Tcp HOM Early adult 6.53×10-06
increased bone mineral density Hgsnatem4(IMPC)Tcp HOM Early adult 5.94×10-10
increased circulating potassium level Hgsnatem4(IMPC)Tcp HOM Early adult 2.36×10-07
decreased total body fat amount Hgsnatem4(IMPC)Tcp HOM Early adult 9.09×10-08
increased circulating phosphate level Hgsnatem4(IMPC)Tcp HOM Early adult 8.22×10-05
increased bone mineral content Hgsnatem4(IMPC)Tcp HOM Early adult 2.66×10-11
hypoactivity Hgsnatem4(IMPC)Tcp HOM Early adult 2.75×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
9 Images
Histopathology
11 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Brain - intracellular and extracellular accumulation Hgsnatem4(IMPC)Tcp HOM Early adult
Liver - process of degenerative change Hgsnatem4(IMPC)Tcp HOM Early adult
Uterus - process of degenerative change Hgsnatem4(IMPC)Tcp HOM Early adult
Brain - process of degenerative change Hgsnatem4(IMPC)Tcp HOM Early adult

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MGI Allele Allele Type Produced
Hgsnatem4(IMPC)Tcp Indel causing a Frameshift Mutation Mice, Tissue
Hgsnattm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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