Gene: Hgsnat

Name
heparan-alpha-glucosaminide N-acetyltransferase
MGI ID
MGI:1196297
Synonyms
Tmem76 D8Ertd354e 9430010M12Rik
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal lung morphology Hgsnatem4(IMPC)Tcp HOM postnatal 0.00
increased circulating potassium level Hgsnatem4(IMPC)Tcp HOM postnatal 2.56×10-09
abnormal bone structure Hgsnatem4(IMPC)Tcp HOM postnatal 1.38×10-08
decreased circulating serum albumin level Hgsnatem4(IMPC)Tcp HOM postnatal 6.54×10-05
increased bone mineral density Hgsnatem4(IMPC)Tcp HOM postnatal 5.94×10-10
increased lean body mass Hgsnatem4(IMPC)Tcp HOM postnatal 3.81×10-08
enlarged lymph nodes Hgsnatem4(IMPC)Tcp HOM postnatal 0.00
short tibia Hgsnatem4(IMPC)Tcp HOM postnatal 6.53×10-06
increased circulating alkaline phosphatase level Hgsnatem4(IMPC)Tcp HOM postnatal 1.50×10-05
increased circulating phosphate level Hgsnatem4(IMPC)Tcp HOM postnatal 1.26×10-06
increased bone mineral content Hgsnatem4(IMPC)Tcp HOM postnatal 2.66×10-11
decreased total body fat amount Hgsnatem4(IMPC)Tcp HOM postnatal 9.09×10-08
enlarged urinary bladder Hgsnatem4(IMPC)Tcp HOM postnatal 0.00
abnormal behavior Hgsnatem4(IMPC)Tcp HOM postnatal 5.97×10-05
hypoactivity Hgsnatem4(IMPC)Tcp HOM postnatal 2.02×10-05

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Histopathology
11 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Gross Pathology and Tissue Collection
9 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Brain - process of degenerative change Hgsnatem4(IMPC)Tcp HOM postnatal
Uterus - process of degenerative change Hgsnatem4(IMPC)Tcp HOM postnatal
Liver - process of degenerative change Hgsnatem4(IMPC)Tcp HOM postnatal
Brain - intracellular and extracellular accumulation Hgsnatem4(IMPC)Tcp HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Hgsnatem4(IMPC)Tcp Indel causing a Frameshift Mutation Mice, Tissue
Hgsnattm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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