Gene: Kcnj10

Name
potassium inwardly-rectifying channel, subfamily J, member 10
MGI ID
MGI:1194504
Synonyms
Kir4.1 BIRK-1 BIR10 Kir4.1 Kir1.2
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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean platelet volume Kcnj10tm1b(KOMP)Wtsi HET postnatal 1.90×10-08
decreased basophil cell number Kcnj10tm1b(KOMP)Wtsi HET postnatal 2.52×10-08
preweaning lethality, complete penetrance Kcnj10tm1b(KOMP)Wtsi HOM n/a 0.00
decreased mean platelet volume Kcnj10tm1b(KOMP)Wtsi HET postnatal 1.90×10-08

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (2/2) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (2/2) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485)  (2/2) N/A
Forelimb 1  (1/485) N/A
Hand 1  (1/485) N/A
Head 1  (5/485)  (2/2) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485)  (2/2) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485)  (2/2) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485)  (2/2) N/A
Tail somite 1  (1/485) N/A

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Lateral Orientation
11 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Adult LacZ: LacZ Images Wholemount
9 Images
X-ray: XRay Images Dorso Ventral
11 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Kcnj10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Kcnj10tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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