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Genes Phenotypes

Gene: Celsr1

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Name
cadherin, EGF LAG seven-pass G-type receptor 1
MGI ID
MGI:1100883
Synonyms
Scy Crsh crash Adgrc1
Viability
Homozygous - Subviable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (128) All data table (691)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
corneal opacity Celsr1Crsh HET Early adult 2.56×10-05
abnormal snout morphology Celsr1Scy HET Early adult 6.48×10-10
increased lean body mass Celsr1Scy HET Early adult 2.67×10-08
increased circulating cholesterol level Celsr1Scy HET Early adult 4.78×10-06
abnormal startle reflex Celsr1Scy HET Early adult 3.35×10-05
decreased circulating cholesterol level Celsr1Scy HET Early adult 5.62×10-05
preweaning lethality, incomplete penetrance Celsr1em1(IMPC)Mbp HOM Early adult 0.00
increased total body fat amount Celsr1Scy HET Early adult 4.45×10-07
abnormal head morphology Celsr1Crsh HET Early adult 1.26×10-11
increased circulating HDL cholesterol level Celsr1Scy HET Early adult 9.37×10-06
decreased prepulse inhibition Celsr1Scy HET Early adult 2.32×10-05

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 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Celsr1em1(IMPC)Mbp Exon Deletion Mice
Celsr1tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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