Prss12 | serine protease 12 neurotrypsin (motopsin)
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system
14 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
enlarged thymus | 1 supporting dataset | Prss12em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
abnormal thymus morphology | 1 supporting dataset | Prss12em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
abnormal auditory brainstem response | 1 supporting dataset | Prss12em1(IMPC)Ccpcz | homozygote | Early adult | 7.81x10-4 | ||
abnormal eye morphology | 1 supporting dataset | Prss12em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
decreased body weight | 1 supporting dataset | Prss12em1(IMPC)Ccpcz | homozygote | Early adult | 7.62x10-5 | ||
increased circulating lactate dehydrogenase level | 1 supporting dataset | Prss12em1(IMPC)Ccpcz | homozygote | Early adult | 5.05x10-6 |
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External links
No external links available for Prss12.
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Prss12em1(IMPC)Ccpcz | Exon Deletion | | mouse |
Prss12tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Prss12tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |