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Gene: Nmbr MGI:1100525

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
neuromedin B receptor
Synonyms:
N/A

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Nmbr mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Nmbr by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Fever, Familial Lifelong Persistent
Fever OMIM:228400
Bacterial Susceptibility Due To Tlr Signaling Pathway Deficiency
Fever ORPHA:183713
Familial Cold Autoinflammatory Syndrome 4
Fever OMIM:616115
Anhidrosis, Isolated, With Normal Sweat Glands
Heat intolerance OMIM:106190
Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Irf8 Deficiency
Fever ORPHA:319600
Malignant Hyperthermia, Susceptibility To, 4
Malignant hyperthermia OMIM:600467
Sudden Infant Death Syndrome
Malignant hyperthermia OMIM:272120
Pontiac Fever
Fever ORPHA:99748
Cyclic Neutropenia
Fever OMIM:162800
Macrophagic Myofasciitis
Fever ORPHA:592
Tuberculosis
Fever ORPHA:3389
Progressive Nodular Histiocytosis
Fever ORPHA:158022
Deafness, Autosomal Dominant 34, With Or Without Inflammation
Fever, Periodic fever OMIM:617772
Hyperthermia, Cutaneous, With Headaches And Nausea
Fever OMIM:145590
Periodic Fever, Menstrual Cycle-Dependent
Fever OMIM:614674
Chronic Recurrent Multifocal Osteomyelitis 3
Fever OMIM:259680
Malignant Hyperthermia, Susceptibility To, 5
Fever, Malignant hyperthermia OMIM:601887
Digital Extensor Muscle Aplasia-Polyneuropathy
Abnormality of temperature regulation, Heat intolerance ORPHA:2926
Hypohidrosis With Abnormal Palmar Dermal Ridges
Fever OMIM:241120
Encephalopathy, Acute, Infection-Induced, Susceptibility To, 4
Fever OMIM:614212
Spinocerebellar Ataxia Type 3
Abnormality of temperature regulation ORPHA:98757
Pfapa Syndrome
Abnormality of temperature regulation ORPHA:42642
Joubert Syndrome 35
Abnormality of temperature regulation OMIM:618161
Beta-Thalassemia
Abnormality of temperature regulation ORPHA:848
Hypotonia, Hypoventilation, Impaired Intellectual Development, Dysautonomia, Epilepsy, And Eye Abnormalities
Fever, Abnormality of temperature regulation, Hypothermia OMIM:618493
Neurodegeneration, Childhood-Onset, With Hypotonia, Respiratory Insufficiency, And Brain Imaging Abnormalities
Abnormality of temperature regulation OMIM:619173
Machado-Joseph Disease Type 1
Abnormality of temperature regulation ORPHA:276238
Machado-Joseph Disease Type 2
Abnormality of temperature regulation ORPHA:276241
Machado-Joseph Disease Type 3
Abnormality of temperature regulation ORPHA:276244
Stuve-Wiedemann Syndrome 1
Fever, Abnormality of temperature regulation, Recurrent fever OMIM:601559
Chronic Mucocutaneous Candidiasis
Abnormality of temperature regulation ORPHA:1334
Cockayne Syndrome Type 1
Abnormality of temperature regulation ORPHA:90321
Ulnar-Mammary Syndrome
Abnormality of temperature regulation ORPHA:3138
Central Hypoventilation Syndrome, Congenital, 1
Abnormality of temperature regulation OMIM:209880
Deeah Syndrome
Abnormality of temperature regulation OMIM:619004
Acute Transverse Myelitis
Fever, Abnormality of temperature regulation ORPHA:139417
Autosomal Recessive Malignant Osteopetrosis
Abnormality of temperature regulation ORPHA:667
Ichthyosis Follicularis-Alopecia-Photophobia Syndrome
Abnormality of temperature regulation, Heat intolerance ORPHA:2273

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Nmbr

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Nmbr.

No publications found that use IMPC mice or data for Nmbr.

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