Gene: Twf1

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Name
twinfilin actin binding protein 1
MGI ID
MGI:1100520
Synonyms
Twinfilin-1 Ptk9 A6 actin monomer-binding protein twinfilin
Viability
N/A
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal coat/hair pigmentation Twf1tm1a(EUCOMM)Wtsi HOM Early adult 6.43×10-06
decreased body weight Twf1tm1a(EUCOMM)Wtsi HOM Early adult 1.27×10-05
decreased circulating alkaline phosphatase level Twf1tm1a(EUCOMM)Wtsi HOM Early adult 1.06×10-05
decreased effector memory CD4-positive, alpha-beta T cell number Twf1tm1a(EUCOMM)Wtsi HOM Early adult 6.13×10-05
abnormal skin condition Twf1tm1a(EUCOMM)Wtsi HOM Early adult 1.37×10-07
increased effector memory CD4-positive, alpha-beta T cell number Twf1tm1a(EUCOMM)Wtsi HOM Early adult 6.13×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images

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 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Twf1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Twf1tm46454(L1L2_gt1) Targeting vectors
Twf1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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