Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Pnntm1.1(KOMP)Vlcg HOM n/a 0.00
embryonic lethality prior to tooth bud stage Pnntm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
embryonic lethality prior to organogenesis Pnntm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2) N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 8  (6/485)  (2/8) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 8  (1/485)  (2/8) N/A
Embryo 8  (1/485)  (2/8) N/A
Eye 8  (1/485)  (2/8) N/A
Foot 8  (1/485)  (2/8) N/A
Forebrain 8  (1/485)  (2/8) N/A
Forelimb 8  (1/485)  (2/8) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 8  (1/485)  (2/8) N/A
Head 8  (5/485)  (2/8) N/A
Heart 8  (1/485)  (2/8) N/A
Hindbrain 8  (6/485)  (2/8) N/A
Hindlimb 8  (1/485)  (2/8) N/A
Liver 8  (1/485)  (2/8) N/A
Lung 8  (1/485)  (2/8) N/A
Mandibular process 8  (1/485)  (2/8) N/A
Maxillary process 8  (1/485)  (2/8) N/A
Midbrain 8  (1/485)  (2/8) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 8  (1/485)  (2/8) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 8  (1/485)  (2/8) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 8  (1/485)  (2/8) N/A
Tail somite 8  (1/485)  (2/8) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Gross Pathology and Tissue Collection
6 Images
Combined SHIRPA and Dysmorphology
1 Images
Eye Morphology: Images Ophthalmoscopy
8 Images
Adult LacZ: LacZ Images Section
8 Images
Eye Morphology: Images Slit Lamp
2 Images
Embryo LacZ: LacZ images wholemount
23 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental and structural abnormality Pnntm1.1(KOMP)Vlcg HET postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Pnntm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Pnntm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Pnntm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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