Genes Phenotypes

Gene: Cdk12

Name
cyclin-dependent kinase 12
MGI ID
MGI:1098802
Synonyms
Crkrs D11Ertd752e 1810022J16Rik Crk7
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (209) All data table (295)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating serum albumin level Cdk12em1(IMPC)Tcp HET postnatal 2.25×10-05
decreased circulating HDL cholesterol level Cdk12em1(IMPC)Tcp HET postnatal 7.70×10-06
embryonic lethality prior to organogenesis Cdk12em1(IMPC)Tcp HOM embryonic day 9.5 0.00
abnormal embryo size Cdk12em1(IMPC)Tcp HET embryonic day 9.5 0.00
preweaning lethality, complete penetrance Cdk12em1(IMPC)Tcp HOM n/a 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cdk12tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cdk12tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Cdk12em1(IMPC)Tcp Exon Deletion Mice, Tissue

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