IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Nrap by phenotypic similarity.
|Major Affective Disorder 2||
||Bipolar affective disorder||OMIM:309200|
||Bipolar affective disorder||OMIM:152420|
|Major Depressive Disorder||
|Panic Disorder 1||
|Major Affective Disorder 1||
|Intellectual Developmental Disorder, Autosomal Recessive 25||
|Severe Primary Trimethylaminuria||
||Aggressive behavior, Anxiety, Emotional lability, Low self esteem, Depression, Negative affectivity||ORPHA:468726|
||Skin-picking, Depression, Anxiety||OMIM:164230|
|Intellectual Developmental Disorder, Autosomal Recessive 59||
|Dystonia 11, Myoclonic||
||Agoraphobia, Panic attack, Depression, Anxiety||OMIM:159900|
||Abnormal fear/anxiety-related behavior, Separation insecurity, Emotional lability, Depression, Ag...||ORPHA:66624|
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|MGI Allele||Allele Type||Produced|
|Nraptm2a(KOMP)Mbp||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors, ES Cells|
|Nraptm1e(KOMP)Wtsi||Targeted, non-conditional allele||ES Cells|
|Nraptm1a(KOMP)Mbp||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors, ES Cells|
|Nraptm93060(L1L2_Pgk_P)||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors|
|Nraptm1e(KOMP)Mbp||Targeted, non-conditional allele||ES Cells|
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