Genes Phenotypes

Gene: Aak1

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Name
AP2 associated kinase 1
MGI ID
MGI:1098687
Synonyms
D6Ertd245e 5530400K14Rik
Viability
Homozygous - Subviable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (15) Measurements chart (245) All data table (345)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating serum albumin level Aak1tm1b(EUCOMM)Hmgu HOM Early adult 8.96×10-06
short tibia Aak1tm1b(EUCOMM)Hmgu HOM Early adult 7.93×10-25
decreased startle reflex Aak1tm1b(EUCOMM)Hmgu HOM Early adult 3.70×10-10
abnormal behavior Aak1tm1b(EUCOMM)Hmgu HOM Early adult 1.04×10-05
abnormal heart left ventricle morphology Aak1tm1b(EUCOMM)Hmgu HOM Early adult 3.80×10-05
decreased circulating total protein level Aak1tm1b(EUCOMM)Hmgu HOM Early adult 7.93×10-07
hyperactivity Aak1tm1b(EUCOMM)Hmgu HOM Early adult 5.24×10-05
increased mean corpuscular volume Aak1tm1b(EUCOMM)Hmgu HOM Early adult 3.16×10-06
increased prepulse inhibition Aak1tm1b(EUCOMM)Hmgu HOM Early adult 6.48×10-05
preweaning lethality, incomplete penetrance Aak1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
increased or absent threshold for auditory brainstem response Aak1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
decreased grip strength Aak1tm1b(EUCOMM)Hmgu HOM Early adult 1.41×10-16
increased vertical activity Aak1tm1b(EUCOMM)Hmgu HOM Early adult 9.27×10-16
abnormal retinal outer nuclear layer morphology Aak1tm1b(EUCOMM)Hmgu HOM Early adult 8.09×10-05
increased circulating alkaline phosphatase level Aak1tm1b(EUCOMM)Hmgu HOM Early adult 5.66×10-05

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 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Aak1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Aak1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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