Gene: Aak1

Name
AP2 associated kinase 1
MGI ID
MGI:1098687
Synonyms
D6Ertd245e 5530400K14Rik
Viability
Homozygous - Subviable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean corpuscular volume Aak1tm1b(EUCOMM)Hmgu HOM postnatal 2.65×10-06
decreased circulating total protein level Aak1tm1b(EUCOMM)Hmgu HOM postnatal 7.93×10-07
increased vertical activity Aak1tm1b(EUCOMM)Hmgu HOM postnatal 8.37×10-16
decreased grip strength Aak1tm1b(EUCOMM)Hmgu HOM postnatal 3.38×10-05
increased or absent threshold for auditory brainstem response Aak1tm1b(EUCOMM)Hmgu HOM postnatal 0.00
abnormal behavior Aak1tm1b(EUCOMM)Hmgu HOM postnatal 1.17×10-05
abnormal retinal outer nuclear layer morphology Aak1tm1b(EUCOMM)Hmgu HOM postnatal 8.09×10-05
short tibia Aak1tm1b(EUCOMM)Hmgu HOM postnatal 7.93×10-25
decreased circulating serum albumin level Aak1tm1b(EUCOMM)Hmgu HOM postnatal 8.96×10-06
hyperactivity Aak1tm1b(EUCOMM)Hmgu HOM postnatal 5.68×10-05
increased circulating alkaline phosphatase level Aak1tm1b(EUCOMM)Hmgu HOM postnatal 5.66×10-05
abnormal heart left ventricle morphology Aak1tm1b(EUCOMM)Hmgu HOM postnatal 3.70×10-05
preweaning lethality, incomplete penetrance Aak1tm1b(EUCOMM)Hmgu HOM n/a 0.00

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Filtered by: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
16 Images
X-ray: XRay Images Lateral Orientation
16 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Aak1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Aak1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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