Gene: Adam11

Name
a disintegrin and metallopeptidase domain 11
MGI ID
MGI:1098667
Synonyms
Mdc
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (347) Expression & images (67) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Alanine aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.277 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / LVPWd HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.860 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Bulging eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Creatinine HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.537 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Iris/Pupil HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Mean cell hemoglobin concentration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0644 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Radius HOM 3f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Fibula HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Eosinophil differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.380 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Percentage center time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.477 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Mean platelet volume HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.724 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / LVAWs HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.438 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Shape of vertebrae HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Brachydactyly HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Scapulae HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Lens Opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Periphery distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00738 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Retina (combined) HOM 8f:7m Not processed Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Zygomatic bone HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Calcium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.280 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / HR HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.159 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Shape of ribs HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Hematocrit HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.110 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.852 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Creatine kinase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.121 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.963 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Pupil Dilation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.432 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.929 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Potassium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.991 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Phosphorus HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0882 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Viability Primary Screen / Outcome HOM 76f:98m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / End-Diastolic Diameter HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.957 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Large Unstained Cell (LUC) count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.182 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Lymphocyte cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.128 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.595 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Center distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.908 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Corneal vascularization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Triglycerides HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.549 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Clavicle HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:7m Fisher Exact Test framework 0.000701 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Platelet count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.649 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Digit integrity HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Total protein HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.889 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / Respiration Rate HOM 7f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.618 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Pupil Position HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.428 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Latency to center entry HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.593 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Eyelid closure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Fusion of vertebrae HOM 3f:6m Fisher Exact Test framework 0.0444 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / LVIDd HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.788 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Tibia HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Aspartate aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0147 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Eosinophil cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.163 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.509 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Hemoglobin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.399 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Whole arena resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.187 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Syndactylism HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Lens HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Head size HOM 8f:7m Fisher Exact Test framework 0.0228 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.854 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Center average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.286 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Narrow eye opening HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Sodium HOM 8f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_001_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Adam11tm1b(KOMP)Mbp MRC Harwell Organ Weight / Heart weight HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0131 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0442 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Neutrophil differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.187 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / HDL-cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0451 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Persistence of hyaloid vascular system HOM 8f:7m Fisher Exact Test framework 0.353 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.612 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0192 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Pupil Shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Periphery average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0283 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Processes on vertebrae HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Maxilla/Pre-maxilla HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Lymphocyte differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.102 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / Stroke Volume HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.326 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Monocyte differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.647 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.663 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Number of ribs right HOM 3f:6m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Distance travelled - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0508 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Snout size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Alpha-amylase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0608 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Auditory Brain Stem Response / Click-evoked ABR threshold HOM 4f:0m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Synechia HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Iron HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.809 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Total cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.181 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Periphery permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.133 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Albumin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.148 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.159 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / LVAWd HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.269 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Number of center entries HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.517 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Pelvis HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HOM 8f:7m Fisher Exact Test framework 0.122 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Grip Strength / Forelimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.753 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Eyelid morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Shape of spine HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / LVPWs HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.855 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Mean cell volume HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.176 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Femur HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Cornea HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Center permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.477 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Basophil cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.141 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.838 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / Ejection Fraction HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.461 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Red blood cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00449 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.388 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Iris Pigmentation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.591 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Retinal Blood Vessels HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Mandibles HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Neutrophil cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0117 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Humerus HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Number of digits HOM 3f:6m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.821 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Periphery resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.448 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Ulna HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Organ Weight / Spleen weight HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.165 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Fructosamine HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.644 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Alkaline phosphatase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00348 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Monocyte cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.298 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Teeth HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / End-Systolic Diameter HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.374 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Number of ribs left HOM 3f:6m 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00863 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Fusion between cornea and lens HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Mean corpuscular hemoglobin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0174 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / Cardiac Output HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.130 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / LVIDs HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.207 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00481 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Large Unstained Cell (LUC) differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.331 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Total bilirubin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.564 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Fusion of ribs HOM 3f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.567 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Basophil differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.330 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Center resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0598 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Glucose HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.705 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Retinal Blood Vessels Structure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Joints HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Skull shape HOM 3f:6m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Echo / Fractional Shortening HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.530 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Gait HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / Red blood cell distribution width HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.132 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Ears HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adam11tm1b(KOMP)Mbp MRC Harwell Clinical Chemistry / Chloride HOM 8f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_003_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Adam11tm1b(KOMP)Mbp MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.200 Success
Adam11tm1b(KOMP)Mbp MRC Harwell X-ray / Tibia length HOM 3f:6m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_XRY_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Pupil Light Response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Open Field / Whole arena average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0514 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Eye Morphology / Corneal opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Adam11tm1b(KOMP)Mbp MRC Harwell Hematology / White blood cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0947 Success
Adam11tm1b(KOMP)Mbp MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485)  (1/4) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Dorso Ventral
12 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
5 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Lateral Orientation
12 Images
Adult LacZ: LacZ Images Wholemount
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Adam11tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice
Adam11tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Adam11tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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