Gene: Cyp27b1

Log in to follow
Name
cytochrome P450, family 27, subfamily b, polypeptide 1
MGI ID
MGI:1098274
Synonyms
25-hydroxyvitamin D3 1alpha-hydroxylase P450VD1alpha 1alpha(OH)ase 25(OH)D 1alpha-hydroxylase Cyp40 Cp2b Cyp1 Pddr Vdd1 Vddr Cyp27b P450c1 VddrI
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal vertebrae morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
abnormal ulna morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
increased circulating alkaline phosphatase level Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 1.83×10-39
decreased circulating calcium level Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal joint morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
increased anxiety-related response Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 2.11×10-05
abnormal pelvic girdle bone morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 2.83×10-08
decreased circulating HDL cholesterol level Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 8.15×10-09
hypoactivity Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 8.79×10-16
decreased circulating phosphate level Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 2.28×10-07
increased circulating bilirubin level Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 3.71×10-08
abnormal bone structure Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 2.53×10-30
short tibia Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal tibia morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
decreased exploration in new environment Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 1.33×10-07
decreased bone mineral density Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
decreased circulating glucose level Cyp27b1tm1b(EUCOMM)Hmgu HOM   Early adult 3.90×10-05
decreased circulating cholesterol level Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 1.66×10-13
decreased bone mineral content Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 3.79×10-39
abnormal radius morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
abnormal clavicle morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
abnormal fibula morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
abnormal rib morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
abnormal scapula morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
decreased total body fat amount Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 8.80×10-08
abnormal humerus morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
abnormal femur morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
decreased body length Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 1.16×10-29
decreased vertical activity Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 9.03×10-08
decreased grip strength Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 3.01×10-11
abnormal cranium morphology Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 7.41×10-12
decreased startle reflex Cyp27b1tm1b(EUCOMM)Hmgu HOM Early adult 7.02×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Whole Body Lateral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
Gross Pathology and Tissue Collection
4 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Cyp27b1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Cyp27b1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cyp27b1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter