Gene: Bhlhe40

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Name
basic helix-loop-helix family, member e40
MGI ID
MGI:1097714
Synonyms
eip1 (E47 interaction protein 1) Stra13 CR8 cytokine response gene 8 Clast5 C130042M06Rik Stra14 DEC1 Sharp2 Bhlhb2
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating glycerol level Bhlhe40tm1b(KOMP)Wtsi HOM Early adult 5.54×10-07
increased bone mineral content Bhlhe40tm1b(KOMP)Wtsi HOM   Early adult 1.54×10-05
decreased circulating HDL cholesterol level Bhlhe40tm1b(KOMP)Wtsi HOM Early adult 6.12×10-07
increased mean corpuscular hemoglobin Bhlhe40tm1b(KOMP)Wtsi HOM   Early adult 4.33×10-11
impaired glucose tolerance Bhlhe40tm1b(KOMP)Wtsi HOM Early adult 7.99×10-05
decreased circulating cholesterol level Bhlhe40tm1b(KOMP)Wtsi HOM Early adult 2.71×10-07
decreased fasting circulating glucose level Bhlhe40tm1b(KOMP)Wtsi HOM Early adult 1.10×10-06
decreased circulating calcium level Bhlhe40tm1b(KOMP)Wtsi HOM Early adult 9.72×10-05
convulsive seizures Bhlhe40tm1b(KOMP)Wtsi HOM Early adult 1.84×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Section images
Aorta 2 No  (1/583)  (2/2)  Section images
Bone marrow 2 No  (2/2)  Section images
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583)  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (1/583)  (2/2)  Section images
Cerebellum 2 No  (3/583)  (2/2)  Section images
Cerebral cortex 2 No  (2/583)  (2/2)  Section images
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/583)  (2/2)  Section images
Hippocampus 2 No  (3/583)  (2/2)  Section images
Hypothalamus 2 No  (2/583)  (2/2)  Section images
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2)  Section images
Lymph node 2 No  (1/583)  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (2/2)  Section images
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583)  (2/2)  Section images
Peripheral nervous system 2 No  (2/583)  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (1/583)  (2/2)  Section images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Section images
Small intestine 2 No  (9/583)  (2/2)  Section images
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583)  (2/2)  Section images
Stomach 2 No  (13/583)  (2/2)  Section images
Striatum 2 No  (3/583)  (2/2)  Section images
Submandibular gland 2 No  (2/130)  (2/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (1/583)  (2/2)  Section images
Thyroid gland 2 No  (17/583)  (2/2)  Section images
Trachea 2 No  (3/583)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (1/3) N/A
2  (1/60) N/A
2  (1/505) N/A
2  (1/506)  (2/3)  Wholemount images
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/61) N/A
2  (1/505) N/A
2  (5/505)  (1/3) N/A
2  (1/505)  (2/3) N/A
2  (6/505)  (1/3) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) Image Only N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/75)  (1/3) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/72)  (1/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
18 Images
Sleep Wake: Wake state (bmp file)
10 Images
Original Image
Adult LacZ: LacZ Images Section
47 Images
X-ray: XRay Images Forepaw
17 Images
X-ray: XRay Images Whole Body Lateral Orientation
18 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Eye Morphology: Images Ophthalmoscopy
12 Images
X-ray: XRay Images Skull Lateral Orientation
18 Images
Eye Morphology: Images Slit Lamp
2 Images
Legacy Phenotype Associated Images

View all 55 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Bhlhe40tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Bhlhe40tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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