Ptgis | prostaglandin I2 (prostacyclin) synthase

GeneMGI:1097156Genome BrowserSynonyms: Pgi2, Cyp8a1, +1 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Nervous system Reproductive system Immune system Homeostasis/metabolism Hematopoietic system Endocrine/exocrine gland Renal/urinary system Cardiovascular system Growth/size/body region

11 No significant impact

4 Not tested

Gene metrics:24Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Human diseases caused by Ptgis mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

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IMPC related publications

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Order Mouse and ES Cells

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