Gene: Utp4 MGI:1096573

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Gene Summary

Name:
UTP4 small subunit processome component
Synonyms:
TEG-292,  Tex292,  Cirh1a

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Utp4em1(IMPC)J HOM   Early adult 0.00
abnormal neural tube closure Utp4em1(IMPC)J HET E9.5 0.00
impaired righting response Utp4em1(IMPC)J HET Late adult 2.30×10-07
limb grasping Utp4em1(IMPC)J HET Late adult 6.47×10-08
abnormal coat/ hair morphology Utp4em1(IMPC)J HET Late adult 3.49×10-06
embryonic lethality prior to organogenesis Utp4em1(IMPC)J HOM   E9.5 0.00
absent vibrissae Utp4em1(IMPC)J HET Late adult 1.76×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Combined SHIRPA and Dysmorphology

Images

1 Images

Human diseases caused by Utp4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Utp4 by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Utp4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Utp4.

No publications found that use IMPC mice or data for Utp4.

Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Utp4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Utp4em1(IMPC)J Exon Deletion Mice

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