banner
Genes Phenotypes Help, News, Blog

Gene: Vamp7 MGI:1096399

Log in to follow
Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
vesicle-associated membrane protein 7
Synonyms:
VAMP-7,  Sybl1

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Vamp7 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Vamp7 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
46,Xy Partial Gonadal Dysgenesis
ORPHA:251510

The table below shows human diseases predicted to be associated to Vamp7 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Pandas
Anorexia, Impulsivity, Abnormal fear-induced behavior, Depression, Irritability, Tics, Attention ... ORPHA:66624
Primary Erythromelalgia
Hypothermia ORPHA:90026
Riboflavin Deficiency
Hypothermia OMIM:615026
2-Methylbutyryl-Coa Dehydrogenase Deficiency
Hypothermia OMIM:610006
Developmental And Epileptic Encephalopathy 78
Hypothermia OMIM:618557
Spontaneous Periodic Hypothermia
Hypothermia ORPHA:29822
Coenzyme Q10 Deficiency, Primary, 5
Hypothermia OMIM:614654
Meningococcal Meningitis
Fever, Irritability, Hypothermia, Anorexia ORPHA:33475
Mitochondrial Complex Iv Deficiency, Nuclear Type 13
Hypothermia OMIM:616501
Idiopathic Congenital Hypothyroidism
Hypothermia ORPHA:95717
Bilateral Parasagittal Parieto-Occipital Polymicrogyria
Abnormal fear-induced behavior, Pseudobulbar paralysis, Aggressive behavior ORPHA:208441
Sudden Infant Death-Dysgenesis Of The Testes Syndrome
Hypothermia ORPHA:168593
Mitochondrial Dna Depletion Syndrome 9 (Encephalomyopathic Type With Methylmalonic Aciduria)
Hypothermia OMIM:245400
Rigidity And Multifocal Seizure Syndrome, Lethal Neonatal
Hypothermia OMIM:614498
Periodic Fever, Menstrual Cycle-Dependent
Fever, Increased circulating cortisol level OMIM:614674
Congenital Enterovirus Infection
Fever, Irritability, Hypothermia ORPHA:292
Congenital Hypothyroidism Due To Maternal Intake Of Antithyroid Drugs
Hypothermia ORPHA:226313
Menkes Disease
Hypothermia OMIM:309400
Familial Thyroid Dyshormonogenesis
Hypothermia ORPHA:95716
Timothy Syndrome
Hypothermia OMIM:601005
Aromatic L-Amino Acid Decarboxylase Deficiency
Intermittent hypothermia, Tongue thrusting, Irritability, Emotional lability, Temperature instabi... OMIM:608643
X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome
Hyperactivity, Anorexia, Aggressive behavior, Abnormal fear-induced behavior, Irritability, Abnor... ORPHA:3077
Hypotonia, Hypoventilation, Impaired Intellectual Development, Dysautonomia, Epilepsy, And Eye Abnormalities
Fever, Abnormality of temperature regulation, Hypothermia OMIM:618493
Carnitine-Acylcarnitine Translocase Deficiency
Irritability, Hypothermia ORPHA:159
Sudden Infant Death With Dysgenesis Of The Testes Syndrome
Hypothermia OMIM:608800
Isolated Thyroid-Stimulating Hormone Deficiency
Hypercholesterolemia, Hypothermia, Attention deficit hyperactivity disorder, Depression ORPHA:90674
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Hypothermia, Increased circulating free fatty acid level ORPHA:26793
Alexander Disease
Hypothermia, Depression, Self-injurious behavior, Dysphagia, Emotional lability ORPHA:58
3-Hydroxy-3-Methylglutaric Aciduria
Fever, Hypothermia, Anorexia ORPHA:20
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Fever, Hypothermia, Aggressive behavior, Hyperlipidemia, Depression, Self-injurious behavior, Com... ORPHA:293987
Mitochondrial Complex Iii Deficiency, Nuclear Type 10
Hypothermia OMIM:618775
Ethylene Glycol Poisoning
Addictive alcohol use, Hypothermia, Euphoria ORPHA:31826
Genetic Transient Congenital Hypothyroidism
Hypothermia ORPHA:226316
Combined Oxidative Phosphorylation Deficiency 37
Hypothermia OMIM:618329
Neuroleptic Malignant Syndrome
Fever, Agitation, Hypothermia, Dysphagia ORPHA:94093
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)
Hypothermia OMIM:251880
Adult-Onset Autosomal Dominant Leukodystrophy
Temperature instability, Hypothermia, Dysphagia ORPHA:99027
Hypothyroidism Due To Tsh Receptor Mutations
Hypothermia ORPHA:90673
Dopamine Beta-Hydroxylase Deficiency
Hypothermia ORPHA:230
Mitochondrial Dna-Associated Leigh Syndrome
Fever, Hypothermia, Dysphagia ORPHA:255210
Tbck-Related Intellectual Disability Syndrome
Hypothermia ORPHA:488632
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria
Hypothermia, Aggressive behavior ORPHA:17
Hereditary Sensory And Autonomic Neuropathy Type 4
Nail-biting, Hyperactivity, Unexplained fevers, Impulsivity, Hypothermia, Abnormal emotion, Dysph... ORPHA:642
Orthostatic Hypotension 1
Intermittent hypothermia OMIM:223360
Methylmalonic Acidemia With Homocystinuria, Type Cblc
Hypothermia ORPHA:79282
Marburg Hemorrhagic Fever
Fever, Hypothermia, Anorexia, Aggressive behavior ORPHA:99826
Menkes Disease
Hypothermia ORPHA:565
Occipital Horn Syndrome
Hypothermia, Dysphagia ORPHA:198
Porphyria Due To Ala Dehydratase Deficiency
Abnormal fear-induced behavior, Agitation, Restlessness, Depression ORPHA:100924
Hypothyroidism Due To Deficient Transcription Factors Involved In Pituitary Development Or Function
Hypothermia ORPHA:226307
Hypothyroidism, Congenital, Nongoitrous, 2
Hypothermia OMIM:218700
Gm2 Gangliosidosis, Ab Variant
Abnormal fear-induced behavior, Inappropriate behavior ORPHA:309246
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome
Hypothermia, Stereotypical hand wringing, Dysphagia ORPHA:438213
Sarcoidosis
Fever, Hypothermia ORPHA:797
Rubinstein-Taybi Syndrome Due To 16P13.3 Microdeletion
Hyperactivity, Impulsivity, Aggressive behavior, Abnormal fear-induced behavior, Self-injurious b... ORPHA:353281
Rubinstein-Taybi Syndrome Due To Ep300 Haploinsufficiency
Hyperactivity, Impulsivity, Aggressive behavior, Abnormal fear-induced behavior, Self-injurious b... ORPHA:353284
Rubinstein-Taybi Syndrome Due To Crebbp Mutations
Hyperactivity, Impulsivity, Aggressive behavior, Abnormal fear-induced behavior, Self-injurious b... ORPHA:353277
46,Xy Partial Gonadal Dysgenesis
ORPHA:251510

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Vamp7

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Vamp7.

No publications found that use IMPC mice or data for Vamp7.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter