Gene: Hcn1

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Name
hyperpolarization activated cyclic nucleotide gated potassium channel 1
MGI ID
MGI:1096392
Synonyms
Bcng1 hyperpolarization-activated, cyclic nucleotide-gated K+ 1 C630013B14Rik HAC2
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal locomotor behavior Hcn1em1(IMPC)H HOM Early adult 6.32×10-06
tremors Hcn1em1(IMPC)H HOM Early adult 2.77×10-06
shortened QT interval Hcn1em1(IMPC)H HOM Early adult 8.16×10-10
hypoactivity Hcn1em1(IMPC)H HOM Early adult 1.51×10-06
abnormal gait Hcn1em1(IMPC)H HOM Early adult 6.07×10-18
decreased heart rate Hcn1em1(IMPC)H HOM Early adult 6.26×10-11
decreased threshold for auditory brainstem response Hcn1em1(IMPC)H HOM Early adult 7.16×10-05
increased heart weight Hcn1em1(IMPC)H HOM Early adult 7.48×10-06
abnormal behavior Hcn1em1(IMPC)H HOM Early adult 7.37×10-07
prolonged RR interval Hcn1em1(IMPC)H HOM Early adult 1.02×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Hcn1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Hcn1em1(IMPC)H Exon Deletion Mice
Hcn1em2(IMPC)H Exon Deletion Mice

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