Gene: Nrxn1

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Name
neurexin I
MGI ID
MGI:1096391
Synonyms
alpha-latrotoxin receptor (calcium-dependent) neurexin I beta neurexin I alpha neurexin I beta neurexin I beta neurexin I alpha neurexin I alpha 1700062G21Rik A230068P09Rik 9330127H16Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating alkaline phosphatase level Nrxn1tm1b(KOMP)Wtsi HOM Early adult 8.00×10-08
increased circulating aspartate transaminase level Nrxn1tm1b(KOMP)Wtsi HOM   Early adult 8.06×10-05
decreased pulmonary respiratory rate Nrxn1tm1b(KOMP)Wtsi HOM   Early adult 2.00×10-05
decreased circulating HDL cholesterol level Nrxn1tm1b(KOMP)Wtsi HOM Early adult 2.23×10-09
decreased grip strength Nrxn1tm1b(KOMP)Wtsi HOM   Early adult 2.50×10-07
tremors Nrxn1tm1b(KOMP)Wtsi HET   Early adult 3.48×10-05
impaired glucose tolerance Nrxn1tm1b(KOMP)Wtsi HOM   Early adult 1.73×10-05
decreased circulating cholesterol level Nrxn1tm1b(KOMP)Wtsi HOM Early adult 8.46×10-12
decreased circulating serum albumin level Nrxn1tm1b(KOMP)Wtsi HOM Early adult 6.28×10-05
increased circulating amylase level Nrxn1tm1b(KOMP)Wtsi HET Early adult 2.56×10-06
abnormal bone structure Nrxn1tm1b(KOMP)Wtsi HOM Early adult 3.50×10-05
decreased circulating total protein level Nrxn1tm1b(KOMP)Wtsi HOM Early adult 2.39×10-05
increased lean body mass Nrxn1tm1b(KOMP)Wtsi HET Early adult 4.07×10-05
decreased fasting circulating glucose level Nrxn1tm1b(KOMP)Wtsi HOM Early adult 4.73×10-05
tremors Nrxn1tm1b(KOMP)Wtsi HOM Early adult 7.12×10-09
decreased total body fat amount Nrxn1tm1b(KOMP)Wtsi HOM Early adult 1.78×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584)  (2/2)  Wholemount images
2 No  (1/584) N/A
2 No N/A
2 No  (4/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (7/408) N/A
2 No N/A
2 No N/A
2 No  (2/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (21/584) N/A
2 No  (10/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (2/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584) N/A
2 No N/A
2 No  (5/584) N/A
2 No  (1/562) N/A
2 No  (2/584) N/A
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (12/584) N/A
2 No N/A
2 No  (1/584)  (1/2) N/A
2 No  (9/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (3/584) N/A
2 No  (12/584) N/A
2 No  (3/584) N/A
2 No  (6/584)  (1/2)  Wholemount images
2 No  (1/584) N/A
2 No  (16/584) N/A
2 No  (3/584) N/A
2 No N/A
2 No N/A
2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Echo: M-Mode Images
64 Images
X-ray: XRay Images Whole Body Dorso Ventral
26 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
26 Images
X-ray: XRay Images Whole Body Lateral Orientation
25 Images
Adult LacZ: LacZ Images Wholemount
7 Images
X-ray: XRay Images Skull Lateral Orientation
1 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nrxn1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nrxn1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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