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Gene: Psme3 MGI:1096366

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
Synonyms:
PA28gamma,  pa28g,  Ki,  REGgamma

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Psme3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Psme3 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Immunodeficiency, Partial Combined, With Absence Of Hla Determinants And Beta-2-Microglobulin From Lymphocytes
Recurrent bacterial infections, T lymphocytopenia, Recurrent candida infections OMIM:242870
Immunodeficiency 13
Lymphopenia, Recurrent shingles, Recurrent upper respiratory tract infections, Recurrent pneumoni... OMIM:615518
Growth Hormone Deficiency, Isolated Partial
Postnatal growth retardation, Short stature OMIM:615925
Intrauterine Growth Retardation With Increased Mitomycin C Sensitivity
Postnatal growth retardation, Intrauterine growth retardation OMIM:600546
Immunodeficiency 54
Recurrent respiratory infections, Short stature, Recurrent viral infections, Postnatal growth ret... OMIM:609981
Growth Hormone Insensitivity Syndrome With Immune Dysregulation 2, Autosomal Dominant
Postnatal growth retardation, Short stature, Delayed puberty, Recurrent infections OMIM:618985
Immunodeficiency 55
Absent natural killer cells, Short stature, Postnatal growth retardation, Recurrent infections, N... OMIM:617827
Fanconi Anemia, Complementation Group E
Pancytopenia, Short stature, Thrombocytopenia, Prolonged G2 phase of cell cycle, Reticulocytopeni... OMIM:600901
Fanconi Anemia, Complementation Group C
Pancytopenia, Short stature, Thrombocytopenia, Prolonged G2 phase of cell cycle, Reticulocytopeni... OMIM:227645
Fanconi Anemia, Complementation Group A
Pancytopenia, Short stature, Thrombocytopenia, Prolonged G2 phase of cell cycle, Reticulocytopeni... OMIM:227650
Fanconi Anemia, Complementation Group D2
Pancytopenia, Short stature, Thrombocytopenia, Prolonged G2 phase of cell cycle, Reticulocytopeni... OMIM:227646

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Psme3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Psme3.

No publications found that use IMPC mice or data for Psme3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Psme3tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Psme3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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