Genes Phenotypes

Gene: Sema3f

Name
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
MGI ID
MGI:1096347
Synonyms
Sema IV Semak
Viability
Homozygous - Subviable
Other links
MGI   Ensembl  
Significant phenotypes (14) All measurements (244) Expression & images (67) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 4.18×10-09
limb grasping Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 6.03×10-10
preweaning lethality, incomplete penetrance Sema3ftm1b(EUCOMM)Hmgu HOM n/a 0.00
abnormal bone structure Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 3.65×10-06
abnormal nail morphology Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 1.71×10-05
decreased circulating serum albumin level Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 7.62×10-06
decreased bone mineral density Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 9.89×10-08
decreased bone mineral content Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 4.07×10-09
cataract Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 1.13×10-05
abnormal gait Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 2.09×10-07
hypoactivity Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 6.45×10-05
increased circulating iron level Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 1.15×10-06
decreased total body fat amount Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 4.41×10-06
decreased circulating total protein level Sema3ftm1b(EUCOMM)Hmgu HOM postnatal 1.51×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (6)
Cerebral Cortex expression
Striatum expression
Brain expression
Hippocampus expression
Vascular System expression
MA:0000185
MA:0000891
MA:0000168
MA:0000191
MA:0002718
digestive system (3)
Large Intestine expression
MA:0000333
endocrine system (1)
Trachea expression
Thyroid gland expression
MA:0000441
MA:0000129
immune system (1)
Thymus expression
MA:0000142
integumental system (1)
Skin expression
MA:0000151
nervous system (6)
Cerebral Cortex expression
Striatum expression
Brain expression
Hippocampus expression
Vascular System expression
MA:0000185
MA:0000891
MA:0000168
MA:0000191
MA:0002718
postnatal mouse (20)
Cerebral Cortex expression
Striatum expression
Brain expression
Hippocampus expression
Vascular System expression
MA:0000185
MA:0000891
MA:0000168
MA:0000191
MA:0002718
reproductive system (2)
Oviduct expression
MA:0000385
respiratory system (3)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (1)
Vascular System expression
Cartilage tissue no expression
Peripheral Nervous System expression
MA:0002718
MA:0000104
MA:0000218
trunk (10)
Kidney expression
MA:0000368
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (4/4) N/A
Ear 2  (1/485)  (2/4) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (4/4) N/A
Foot 2  (1/485)  (4/4) N/A
Forebrain 2  (1/485)  (4/4) N/A
Forelimb 2  (1/485)  (4/4) N/A
Hand 2  (1/485)  (4/4) N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485)  (3/4) N/A
Hindlimb 2  (1/485)  (4/4) N/A
Liver 2  (1/485)  (1/4) N/A
Lung 2  (1/485)  (1/4) N/A
Mandibular process 2  (1/485)  (2/4) N/A
Maxillary process 2  (1/485)  (2/4) N/A
Midbrain 2  (1/485)  (4/4) N/A
Oral cavity 2  (1/485)  (2/4) N/A
Skin 2  (1/485)  (2/4) N/A
Tail 2  (1/485)  (4/4) N/A
Tail somite 2  (1/485)  (2/4) N/A

 Associated Images

Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
7 Images
Adult LacZ: LacZ Images Wholemount
20 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sema3ftm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice
Sema3ftm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sema3ftm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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