Gene: Sema3f

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Name
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
MGI ID
MGI:1096347
Synonyms
Sema IV Semak
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal gait Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 2.30×10-07
limb grasping Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 2.36×10-10
cataract Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 1.41×10-05
decreased circulating total protein level Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 3.83×10-05
decreased circulating serum albumin level Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 5.49×10-05
tremors Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 8.45×10-05
increased startle reflex Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 3.02×10-14
decreased exploration in new environment Sema3ftm1b(EUCOMM)Hmgu HOM   Early adult 4.16×10-05
abnormal nail morphology Sema3ftm1b(EUCOMM)Hmgu HOM   Early adult 1.23×10-05
preweaning lethality, incomplete penetrance Sema3ftm1b(EUCOMM)Hmgu HOM   Early adult 0.00
increased circulating iron level Sema3ftm1b(EUCOMM)Hmgu HOM Early adult 2.51×10-07

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584) N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No N/A
2 No  (4/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (7/408)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No N/A
2 No  (2/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (21/584)  (2/2)  Wholemount images
2 No  (10/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (1/584) N/A
2 No N/A
2 No  (2/584)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/584) N/A
2 No  (1/2)  Wholemount images
2 No  (5/584) N/A
2 No  (1/562) N/A
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (12/584) N/A
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (9/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (3/584) N/A
2 No  (12/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (6/584)  (1/2)  Wholemount images
2 No  (1/584)  (2/2)  Wholemount images
2 No  (16/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No N/A
2 No  (2/2)  Wholemount images
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507)  (4/4) N/A
Ear 2  (1/507)  (2/4) N/A
Embryo 2  (1/508)  (4/4) N/A
Eye 2  (1/507)  (4/4) N/A
Footplate 2  (1/507)  (4/4) N/A
Forebrain 2  (1/507)  (4/4) N/A
Forelimb 2  (1/507)  (4/4) N/A
Handplate 2  (1/507)  (4/4) N/A
Head 2  (5/507)  (4/4) N/A
Heart 2  (1/507)  (2/4) N/A
Hindbrain 2  (6/507)  (3/4) N/A
Hindlimb 2  (1/507)  (4/4) N/A
Liver 2  (1/502)  (1/4) N/A
Lung 2  (1/502)  (1/4) N/A
Mandibular process 2  (1/507)  (2/4) N/A
Maxillary process 2  (1/507)  (2/4) N/A
Midbrain 2  (1/507)  (4/4) N/A
Oral cavity 2  (1/502)  (2/4) N/A
Skin 2  (1/507)  (2/4) N/A
Tail 2  (1/507)  (4/4) N/A
Tail somite group 2  (1/507)  (2/4) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
20 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
7 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sema3ftm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Sema3ftm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice
Sema3ftm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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