Gene: Atp6v1b2

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ATPase, H+ transporting, lysosomal V1 subunit B2
Atp6b2 HO57
Embryo viewer
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Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased hemoglobin content Atp6v1b2tm1b(KOMP)Wtsi HET Early adult 1.36×10-08
decreased mean corpuscular hemoglobin Atp6v1b2tm1b(KOMP)Wtsi HET Early adult 4.28×10-16
decreased mean corpuscular hemoglobin concentration Atp6v1b2tm1b(KOMP)Wtsi HET Early adult 3.12×10-06
embryonic lethality prior to organogenesis Atp6v1b2tm1b(KOMP)Wtsi HOM E9.5 0.00
preweaning lethality, complete penetrance Atp6v1b2tm1b(KOMP)Wtsi HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Atp6v1b2tm1b(KOMP)Wtsi HOM E12.5 0.00
small lymph nodes Atp6v1b2tm1b(KOMP)Wtsi HET Early adult 0.00
small adrenal glands Atp6v1b2tm1b(KOMP)Wtsi HET Early adult 0.00
decreased mean corpuscular volume Atp6v1b2tm1b(KOMP)Wtsi HET Early adult 7.57×10-06

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Viewing: all phenotypes
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Viewing: all phenotypes


IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 5  (1/61) N/A
Brain 6  (6/504) N/A
Central nervous system ganglion 5  (1/70) N/A
Ear 6  (1/504) N/A
Embryo 6  (1/505)  (4/6) N/A
Eye 6  (1/504) N/A
Foot 6  (1/504) N/A
Forebrain 6  (1/504) N/A
Forelimb 6  (1/504) N/A
Gut 5  (1/56) N/A
Hand 6  (1/503) N/A
Head 6  (5/504) N/A
Heart 6  (1/504)  (4/6) N/A
Hindbrain 6  (6/504) N/A
Hindlimb 6  (1/503) N/A
Liver 6  (1/504) N/A
Lung 6  (1/500) N/A
Mandibular process 6  (1/504) N/A
Maxillary process 6  (1/504) N/A
Midbrain 6  (1/504) N/A
Nose 5  (1/70) N/A
Oral cavity 6  (1/504) N/A
Skeleton 5  (1/70) N/A
Skin 6  (1/504) N/A
Spinal cord 5  (1/69) N/A
Tail 6  (1/504) N/A
Tail somite 6  (1/504) N/A
Trachea 5  (1/56) N/A
Urinary system 5  (1/56)  (4/5) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
86 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
32 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
16 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Slit Lamp
7 Images
Eye Morphology: Images Ophthalmoscopy
2 Images

 Disease Models

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Phenotype Allele Zygosity Sex Life Stage
Spleen - MPATH diagnostic term extramedullary hemopoiesis Atp6v1b2tm1b(KOMP)Wtsi HET Early adult
Spleen - hyperplasia Atp6v1b2tm1b(KOMP)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Atp6v1b2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Atp6v1b2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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