Gene: Barx2

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
corneal vascularization Barx2tm1b(EUCOMM)Hmgu HOM postnatal 1.72×10-09
narrow eye opening Barx2tm1b(EUCOMM)Hmgu HOM postnatal 2.16×10-20
abnormal cornea morphology Barx2tm1b(EUCOMM)Hmgu HOM postnatal 1.25×10-16
corneal opacity Barx2tm1b(EUCOMM)Hmgu HOM postnatal 1.21×10-13
preweaning lethality, incomplete penetrance Barx2tm1b(EUCOMM)Hmgu HOM n/a 0.00
absent vibrissae Barx2tm1b(EUCOMM)Hmgu HOM postnatal 9.67×10-07
abnormal tail morphology Barx2tm1b(EUCOMM)Hmgu HOM postnatal 2.11×10-09
abnormal gait Barx2tm1b(EUCOMM)Hmgu HOM postnatal 6.21×10-05
abnormal eyelid morphology Barx2tm1b(EUCOMM)Hmgu HOM postnatal 2.16×10-20
abnormal vertebrae morphology Barx2tm1b(EUCOMM)Hmgu HOM postnatal 4.43×10-06
abnormal coat/hair pigmentation Barx2tm1b(EUCOMM)Hmgu HOM postnatal 5.90×10-12
abnormal retina morphology Barx2tm1b(EUCOMM)Hmgu HOM postnatal 1.73×10-19
eyelids fail to open Barx2tm1b(EUCOMM)Hmgu HOM postnatal 4.62×10-08

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (4/4) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485)  (4/4) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485)  (2/4) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485)  (2/4) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
Echo: M-Mode Images
28 Images
Adult LacZ: LacZ Images Wholemount
9 Images
X-ray: XRay Images Lateral Orientation
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Barx2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Barx2tm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice
Barx2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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