Genes Phenotypes

Gene: Barx2

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Name
BarH-like homeobox 2
MGI ID
MGI:109617
Synonyms
Barx2b 2310006E12Rik
Viability
Homozygous - Subviable
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (247) All data table (434)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal eye morphology Barx2tm1b(EUCOMM)Hmgu HOM Early adult 0.00
corneal vascularization Barx2tm1b(EUCOMM)Hmgu HOM Early adult 1.39×10-10
preweaning lethality, incomplete penetrance Barx2tm1b(EUCOMM)Hmgu HOM Early adult 0.00
eyelids fail to open Barx2tm1b(EUCOMM)Hmgu HOM Early adult 7.21×10-08
narrow eye opening Barx2tm1b(EUCOMM)Hmgu HOM Early adult 4.36×10-19
abnormal tail morphology Barx2tm1b(EUCOMM)Hmgu HOM Early adult 1.44×10-09
abnormal coat/hair pigmentation Barx2tm1b(EUCOMM)Hmgu HOM Early adult 3.66×10-12
abnormal eyelid morphology Barx2tm1b(EUCOMM)Hmgu HOM Early adult 1.21×10-20
absent vibrissae Barx2tm1b(EUCOMM)Hmgu HOM Early adult 7.25×10-07
abnormal gait Barx2tm1b(EUCOMM)Hmgu HOM Early adult 5.95×10-05
corneal opacity Barx2tm1b(EUCOMM)Hmgu HOM Early adult 4.69×10-14
abnormal vertebrae morphology Barx2tm1b(EUCOMM)Hmgu HOM Early adult 3.47×10-06
abnormal cornea morphology Barx2tm1b(EUCOMM)Hmgu HOM Early adult 7.03×10-17

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
digestive system (1)
Stomach expression
Esophagus expression
MA:0000353
MA:0000352
exocrine system (1)
Prostate gland expression
MA:0000404
integumental system (1)
Skin expression
MA:0000151
nervous system (3)
Brain expression
MA:0000168
postnatal mouse (9)
Brain expression
MA:0000168
reproductive system (3)
Oviduct expression
MA:0000385
respiratory system (1)
Lung expression
MA:0000415
trunk (5)
Lung expression
MA:0000415
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504)  (4/4) N/A
Hand 2  (1/503) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503)  (4/4) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504)  (2/4) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504)  (2/4) N/A
Tail 2  (1/504) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
9 Images
Echo: M-Mode Images
28 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Barx2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Barx2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Barx2tm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice

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