Gene: Pld1

Name
phospholipase D1
MGI ID
MGI:109585
Synonyms
Pld1a Pld1b
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - thickness HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - size HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Alanine aminotransferase HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00918 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - shape HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Monocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.336 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Monocyte differential count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / RR HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0140 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - whole body HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Creatinine HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.845 Success
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.212 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - ear HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean cell hemoglobin concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.877 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean cell hemoglobin concentration HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Snout size HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / PR HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0866 Success
Pld1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.616 Success
Pld1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Total cholesterol HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.996 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - size HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Albumin HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.486 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - length HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / HR HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0156 Success
Pld1tm1b(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.288 Success
Pld1tm1b(KOMP)Wtsi UC Davis Indirect Calorimetry / Total food intake HET 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Eosinophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0555 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Eosinophil differential count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean platelet volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.226 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean platelet volume HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Aggression HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.881 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - presence HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.170 Success
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength measurement mean HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - shape HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Startle response HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower teeth appearance HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - back paws HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - shape HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - shape HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean cell volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.428 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean cell volume HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - back HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Pld1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - size HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Basophil cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.669 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Basophil cell count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Calcium HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.807 Success
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0346 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper lip morphology HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00156 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CSD_032_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Red blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.122 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Red blood cell count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Contact righting HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Hematocrit HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.119 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Hematocrit HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - number HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - ear HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.173 Success
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - tail HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - appearance HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.101 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - abdomen HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0736 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00459 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.167 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Phosphorus HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.731 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - shape HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Neutrophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.879 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Neutrophil cell count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tremor HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Viability Primary Screen / Outcome HOM 30f:34m Supplied as data Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - morphology HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - back paws HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Large Unstained Cell (LUC) count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Indirect Calorimetry / Total water intake HET 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 0.632 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Lymphocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0417 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Lymphocyte cell count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head morphology HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / ST HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.111 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - whole body HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.268 Success
Pld1tm1b(KOMP)Wtsi UC Davis Indirect Calorimetry / Respiratory Exchange Ratio HET 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper teeth appearance HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Number of digits HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Triglycerides HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.420 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0637 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - head HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - presence HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Number of lumbar vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Platelet count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.219 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Platelet count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - size HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Alkaline phosphatase HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.620 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - number HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - length HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Monocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0591 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Monocyte cell count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - snout HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Total protein HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.557 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0127 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - position HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - size HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - front paws HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00888 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - head HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean corpuscular hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.959 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Mean corpuscular hemoglobin HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - size HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0192 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Large Unstained Cell (LUC) differential count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - size HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - morphology HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Total bilirubin HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.602 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Aspartate aminotransferase HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0531 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - position HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - length HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Eosinophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.460 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Eosinophil cell count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vocalization HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.780 Success
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.274 Success
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.223 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Hemoglobin HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower lip morphology HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Basophil differential count HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.179 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Basophil differential count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - front paws HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Teeth presence HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.263 Success
Pld1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength normalised against body weight HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head size HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - back HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Glucose HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.298 Success
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - shape HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - number HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00766 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Neutrophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0133 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Neutrophil differential count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Gait HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Red blood cell distribution width HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.417 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Red blood cell distribution width HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / QRS HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.563 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Ears HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - snout HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - number HET 4f:3m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - presence HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / HDL-cholesterol HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.523 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0839 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Insulin Blood Level / Insulin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.187 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.115 Success
Pld1tm1b(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Pld1tm1b(KOMP)Wtsi UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0106 Success
Pld1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Pld1tm1b(KOMP)Wtsi UC Davis X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Lymphocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0118 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / Lymphocyte differential count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / White blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0450 Success
Pld1tm1b(KOMP)Wtsi UC Davis Hematology / White blood cell count HET 1f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - tail HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Mouth morphology HET 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pld1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No  (1/2) N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Pld1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Pld1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pld1tm47048(L1L2_gt1) Targeting vectors

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