Gene: Dnm2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Dnm2tm1.1(KOMP)Vlcg HOM E12.5 0.00
increased neutrophil cell number Dnm2tm1.1(KOMP)Vlcg HET Early adult 4.55×10-05
preweaning lethality, incomplete penetrance Dnm2tm1.1(KOMP)Vlcg HOM Early adult 0.00
embryonic lethality prior to organogenesis Dnm2tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased mean corpuscular hemoglobin Dnm2tm1.1(KOMP)Vlcg HET Early adult 1.47×10-06
decreased mean corpuscular volume Dnm2 HET Early adult 9.18×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No N/A
Brain 2 No  (2/2)  Section images
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (1/2) N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
White adipose tissue 2 No  (2/2)  Section images
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
7 Images
X-ray: XRay Images Whole Body Dorso Ventral
7 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dnm2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Dnm2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Dnm2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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